Evidence mapPaperPMID 34899613Full record

ReviewFrontiers in endocrinology2021

Obesogens: How They Are Identified and Molecular Mechanisms Underlying Their Action.

Nicole Mohajer, Chrislyn Y Du, Christian Checkcinco, Bruce Blumberg

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Definition and diagnostic criteria of clinical obesity.The lancet. Diabetes & endocrinology · 2025
    Review
  10. Article
  11. Article
  12. Environmental Obesogens and Their Perturbations in Lipid Metabolism.Environment & health (Washington, D.C.) · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Inherited Epigenetic Hallmarks of Childhood Obesity Derived from Prenatal Exposure to Obesogens.International journal of environmental research and public health · 2023
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicole MohajerDeparment of Pharmaceutical Sciences, University of California, Irvine, CA, United States.
Chrislyn Y DuDeparment of Developmental and Cell Biology, University of California, Irvine, CA, United States.
Christian CheckcincoDeparment of Developmental and Cell Biology, University of California, Irvine, CA, United States.
Bruce BlumbergDeparment of Pharmaceutical Sciences, University of California, Irvine, CA, United States.
University of California, Irvine · US

Funding

Interactions between prenatal obesogen exposure and Total Western diet lead to a transgenerational thrifty phenotype: functional and epigenomic analysis of effects in fat and liverR01ES031139 · UNIVERSITY OF CALIFORNIA-IRVINE · 2025 to 2025
$461k
NIEHS NIH HHS R01 ES023316NIEHS NIH HHS R01 ES031139
6 · The paper itself

Abstract

Adult and childhood obesity have reached pandemic level proportions. The idea that caloric excess and insufficient levels of physical activity leads to obesity is a commonly accepted answer for unwanted weight gain. This paradigm offers an inconclusive explanation as the world continually moves towards an unhealthier and heavier existence irrespective of energy balance. Endocrine disrupting chemicals (EDCs) are chemicals that resemble natural hormones and disrupt endocrine function by interfering with the body's endogenous hormones. A subset of EDCs called obesogens have been found to cause metabolic disruptions such as increased fat storage,

Indexed as

AdipogenesisAdipose TissueAnimalsEndocrine DisruptorsEnvironmental ExposureEnvironmental PollutantsGastrointestinal MicrobiomeHumansObesitySweetening AgentsEndocrine DisruptorsEnvironmental PollutantsSweetening AgentsadipogenesisEDCendocrine disrupting chemicalMDCmetabolism disrupting chemicalsobesityobesogens

Identifiers

PMID34899613
PMCPMC8655100
OpenAlexW3216024101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.