ArticleAnnals of general psychiatry2021
Mortality gap and physical comorbidity of people with severe mental disorders: the public health scandal.
Article in Annals of general psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Short-, Medium-, and Long-Term Cardiometabolic Outcomes in First-Episode Psychosis: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2026Pooled it
- Barriers and facilitators of accessing primary healthcare for patients with severe mental illness: a mixed-methods systematic review using framework synthesis.BMC psychiatry · 2025Pooled it
- Respiratory disease in people with major depressive disorder: A systematic review and Meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Side Effects of Psychotropic Medications Experienced by a Community Sample of People Living With Severe and Persistent Mental Illness.Health expectations : an international journal of public participation in health care and health policy · 2024Trial
- Experiences of goal planning in Australian community pharmacy settings for people experiencing mental illness: A qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2023Trial
- Evaluating the Utility of a Statewide Pharmacist-Led Psychotropic Medicines Information Service: A Mixed-Methods Study.Community mental health journal · 2026Article
- Psychiatric comorbidities cluster early after onset in MOGAD: a cross-sectional comparative study with MS and NMOSD.Journal of neurology, neurosurgery, and psychiatry · 2026Article
- Mental Health Promotion in the Personal Trainer-Client Relationship: A Cross-Sectional Analysis.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2026Article
- Determinants of Weight Gain in Forensic Psychiatric Care: A Protocol for a Systematic Review and Meta-Analysis.Campbell systematic reviews · 2026Review
- Obesity Prevalence and Associated Factors Among Users of Specialized Community Mental Health Services: An Observational Study.International journal of mental health nursing · 2026Observational
- Prevalence of chronic kidney disease in people with severe mental illness: systematic review and meta-analysis.The British journal of psychiatry : the journal of mental science · 2026Review
- Nurses' attitudes toward physical health care of psychiatric patients scale: development and validation study.BMC nursing · 2026Article
- Patient perspectives on the challenges, obstacles, and opportunities in discussing and managing anhedonia in major depressive disorder (MDD): a focus group study.Annals of general psychiatry · 2026Article
- Expected Competencies and Personal Attributes of Digital Health Navigators to Support Digital Mental Health Care: Focus Group and Interview Study With Patients and Health Care Professionals.JMIR mental health · 2026Article
- Prescribing of glucose-lowering medication to adults with type 2 diabetes by severe mental illness status in Scotland: A cohort study.Diabetes, obesity & metabolism · 2026Article
- Incidence of psychotic disorders by birth cohort: a population-based cohort study in Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- A Qualitative Exploration of the Acceptability of a Supported Self-Management Intervention for People With Type 2 Diabetes and Severe Mental Illness.Journal of diabetes research · 2026Article
- Patient subgroups and shifting incidence trends: an epidemiological profile of registered severe mental disorders in Quzhou, China (1969-2022).Frontiers in public health · 2026Article
- Ascertaining Household-Level Exposure to Air Pollution: Socio-Demographic Patterning and Urban-Rural Differences in People with Schizophrenia and Other Psychotic Disorders and the General Population.International journal of population data science · 2026Article
- Physical health screening for people with severe mental disorders: a best practice implementation project.Revista da Escola de Enfermagem da U S P · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients suffering from severe mental disorders, including schizophrenia, major depression and bipolar disorders, have a reduced life expectancy compared to the general population of up to 10-25 years. This mortality gap requires urgent actions from a public health perspective in order to be reduced. MAIN TEXT: Factors associated with the high mortality rates in patients with severe mental disorders can be grouped into four groups: those related to the patients, to psychiatrists, to other non-psychiatrist medical doctors and to the healthcare system. Each of these factors should become the target of specific and dedicated interventions, in order to reduce the morbidity and mortality rate in patients with severe mental disorders. All these elements contribute to the neglect of physical comorbidity in patients with severe mental. In particular, the long-standing separation of psychiatry from other branches of medicine and the lack of specific training on this issue further contribute to the poor attention dedicated to management of physical comorbidities. Recently, several professional associations have invited national bodies regulating education of healthcare professionals to include the management of physical health of people with severe mental disorders in undergraduate and postgraduate educational programs.
conclusionsThe premature mortality in patients with severe mental disorders is a complex phenomenon resulting by the interaction of several protective and risk factors. Therefore, a multilevel approach is needed, in which the different stakeholders involved in health care provision establish workforces for the long-term management of physical and mental health conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.