Evidence map›Paper›PMID 34903301›Full record

ArticleBMC nutrition2021

Assessment of dietary diversity and nutritional support for children living with HIV in the IeDEA pediatric West African cohort: a non-comparative, feasibility study.

Julie Jesson, Ayoko Ephoevi-Ga, Marie-Hélène Aké-Assi, Sikiratou Koumakpai, Sylvie N'Gbeche, Evelyne Dainguy, Karen Malateste, Hugo Carrié, Marcelline D'Almeida, François Tanoh Eboua and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 4 countries.

Julie JessonFaculté de Médecine Purpan, Inserm U1027, Université Paul Sabatier Toulouse 3, 37 Allées Jules Guesde, 31073, Toulouse Cedex 7, France. julie_jesson@sfu.ca.
Ayoko Ephoevi-GaCHU Sylvanus Olympio, Université de Lomé, Lomé, Togo.
Marie-Hélène Aké-AssiCHU Yopougon, Service Pédiatrie, Abidjan, Côte d'Ivoire.
Sikiratou KoumakpaiCNHU Hubert K. Maga, Cotonou, Bénin.
Sylvie N'GbecheCePReF, Abidjan, Côte d'Ivoire.
Evelyne DainguyCHU Cocody, Service Pédiatrie, Abidjan, Côte d'Ivoire.
Karen MalatesteUniversity of Bordeaux, Inserm, Institut de Recherche pour le Développement (IRD), UMR 1219, Bordeaux, France.
Hugo CarriéFaculté de Médecine Purpan, Inserm U1027, Université Paul Sabatier Toulouse 3, 37 Allées Jules Guesde, 31073, Toulouse Cedex 7, France.
Marcelline D'AlmeidaCNHU Hubert K. Maga, Cotonou, Bénin.
François Tanoh EbouaCHU Yopougon, Service Pédiatrie, Abidjan, Côte d'Ivoire.
Elom TakassiCHU Sylvanus Olympio, Université de Lomé, Lomé, Togo.
Madeleine Amorissani-FolquetCHU Cocody, Service Pédiatrie, Abidjan, Côte d'Ivoire.
Valériane LeroyFaculté de Médecine Purpan, Inserm U1027, Université Paul Sabatier Toulouse 3, 37 Allées Jules Guesde, 31073, Toulouse Cedex 7, France.
IeDEA West African Pediatric Collaboration
Centre Hospitalier Universitaire de Cocody · CICentre Hospitalier Universitaire de Yopougon · CIUniversité Fédérale de Toulouse Midi-Pyrénées · FRCentre Hospitalier Universitaire de Tokoin · TGCentre National Hospitalier et Universitaire Hubert Koutoukou MAGA · BJLaboratoire Epidémiologie et Analyses en Santé Publique : Risques, Maladies Chroniques et Handicaps · FRSociété de Développement des Forêts · CIBordeaux Population Health · FRInserm · FRUniversity of Lomé · TG

Funding

WADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2M
NIAID NIH HHS U01 AI069919NIA NIH HHS U54 AG062334
6 · The paper itself

Abstract

backgroundNutritional care is not optimally integrated into pediatric HIV care in sub-Saharan Africa. We assessed the 6-month effect of a nutritional support provided to children living with HIV, followed in a multicentric cohort in West Africa.

methodsIn 2014-2016, a nutritional intervention was carried out for children living with HIV, aged under 10 years, receiving antiretroviral therapy (ART) or not, in five HIV pediatric cohorts, in Benin, Togo and Côte d'Ivoire. Weight deficiency was assessed using two definitions: wasting (Weight for Height Z-score [WHZ] for children<5 years old or Body-Mass-Index for Age [BAZ] for ≥5 years) and underweight (Weight for Age Z-score [WAZ]) (WHO child growth standards). Combining these indicators, three categories of nutritional support were defined: 1/ children with severe malnutrition (WAZ and/or WHZ/BAZ <-3 Standard Deviations [SD]) were supported with Ready-To-Use Therapeutic Food (RUTF), 2/ those with moderate malnutrition (WAZ and/or WHZ/BAZ = [-3;-2[ SD) were supported with fortified blended flours produced locally in each country, 3/ those non malnourished (WAZ and WHZ/BAZ ≥-2 SD) received nutritional counselling only. Children were followed monthly over 6 months. Dietary Diversity Score (DDS) using a 24h recall was measured at the first and last visit of the intervention.

resultsOverall, 326 children were included, 48% were girls. At baseline, 66% were aged 5-10 years, 91% were on ART, and 17% were severely immunodeficient (CD4 <250 cells/mL or CD4%<15). Twenty-nine (9%) were severely malnourished, 63 (19%) moderately malnourished and 234 (72%) non-malnourished. After 6 months, 9/29 (31%) and 31/63 (48%) recovered from severe and moderate malnutrition respectively. The median DDS was 8 (IQR 7-9) in Côte d'Ivoire and Togo, 6 (IQR 6-7) in Benin. Mean DDS was 4.3/9 (sd 1.2) at first visit, with a lower score in Benin, but with no difference between first and last visit (p=0.907), nor by intervention groups (p-value=0.767).

conclusionsThis intervention had a limited effect on nutritional recovery and dietary diversity improvement. Questions remain on determining appropriate nutritional products, in terms of adherence, proper use for families and adequate energy needs coverage for children living with HIV.

trial registrationPACTR202001816232398 , June 01, 2020, retrospectively registered.

Indexed as

ChildrenCohortHIVMalnutritionNutritional supportWest Africa

Identifiers

PMID34903301
PMCPMC8670202
OpenAlexW4200115577

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.