Evidence map›Paper›PMID 34907346›Full record

ArticleCommunications biology2021

Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression.

Chen Braun, Xiaorong Xu Parks, Haani Qudsi, Coeli M B Lopes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chen BraunAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY, 14642, USA.
Xiaorong Xu ParksAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY, 14642, USA.ORCID http://orcid.org/0000-0003-1001-0440
Haani QudsiAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY, 14642, USA.
Coeli M B LopesAab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY, 14642, USA. coeli_lopes@urmc.rochester.edu.ORCID http://orcid.org/0000-0001-7515-415X
University of Rochester · USUniversity of Rochester Medical Center · US

Funding

cPKC Regulation of Cardiac Potassium ChannelsR01HL114792 · NHLBI · UNIVERSITY OF ROCHESTER · PI LOPES, COELI M. B. · 2013 to 2016
$1.5M
NHLBI NIH HHS R01 HL114792
6 · The paper itself

Abstract

Plasma membrane phosphatidylinositol 4-phosphate (PI4P) is a precursor of PI(4,5)P

Indexed as

AnimalsCell MembraneFemaleKCNQ1 Potassium ChannelPhosphatidylinositol PhosphatesPotassium Channels, Voltage-GatedRatsRats, Sprague-DawleyKcne1 protein, ratKCNQ1 Potassium ChannelKcnq1 protein, ratphosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesPotassium Channels, Voltage-Gated

Identifiers

PMID34907346
PMCPMC8671492
OpenAlexW4200296594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.