Evidence map›Paper›PMID 34911289›Full record

ArticleEuropean journal of translational myology2021

Is relaxation exercise therapy effective in the management of patients with severe arterial hypertension?

Olga D Lebedeva, Abduahat A Achilov, Zilola F Mavlyanova, Alexey V Baranov, Shachnosa A Achilova, Natalia P Sanina, Anatoly D Fesyun, Andrey P Rachin, Maxim Yu Yakovlev, Kirill V Terentev and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06131528 (Effects of Relaxation Breathing Exercises on Cardiovascular Parameters Among Hypertensive Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06131528 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Relaxation Breathing Exercises on Cardiovascular Parameters Among Hypertensive Patients

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled40ConditionsHypertensionArmsRelaxation Breathing Exercises Group, Usual Care Group
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Olga D LebedevaFederal State Budgetary Institution "National medical research center for rehabilitation and balneology", Ministry of Health of Russia, Moscow. lebedeva-od@yandex.ru.
Abduahat A AchilovFederal State Budgetary Institution "Skobelkin State Scientific Center of Laser Medicine Federal Medical and Biological Agency of Russia", Moscow. achilovaa@mail.ru.
Zilola F MavlyanovaSamarkand state medical institution, Samarkand, Uzbekistan. reab.sammi@mail.ru.
Alexey V BaranovFederal State Budgetary Institution "Skobelkin State Scientific Center of Laser Medicine Federal Medical and Biological Agency of Russia", Moscow. gnc_lazmed@fmbamail.ru.
Shachnosa A AchilovaFederal State Budgetary Institution "Skobelkin State Scientific Center of Laser Medicine Federal Medical and Biological Agency of Russia", Moscow. asa316@mail.ru.
Natalia P SaninaState Budgetary Healthcare Institution M. Vladimirsky Moscow Regional Research Clinical Institute. nataliasanina2@yandex.ru.
Anatoly D FesyunFederal State Budgetary Institution "National medical research center for rehabilitation and balneology", Ministry of Health of Russia, Moscow. fesyunad@nmicrk.ru.
Andrey P RachinFederal State Budgetary Institution "National medical research center for rehabilitation and balneology", Ministry of Health of Russia, Moscow. rachinap@nmicrk.ru.
Maxim Yu YakovlevFederal State Budgetary Institution "National medical research center for rehabilitation and balneology", Ministry of Health of Russia, Moscow. masdat@mail.ru.
Kirill V Terentev. Kirillterentev184@gmail.com.
Igor V ReverchukFederal State Autonomous Educational Institution of Higher Education FSAEI HE "Immanuel Kant Baltic Federal University". bios@reverchuk.com.
Alie S VelilyaevaSamarkand state medical institution, Samarkand. alsabvel@mail.ru.
Maria Chiara MaccaronePhysical Medicine and Rehabilitation School, University of Padova, Padua. mariachiara.maccarone@studenti.unipd.it.
Stefano MasieroPhysical Medicine and Rehabilitation School, University of Padova, Padua, Italy; Rehabilitation Unit, Department of Neuroscience, University of Padova, Padua. stef.masiero@unipd.it.
"National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation · RUSamarkand State Medical Institute · UZUniversity of Padua · ITImmanuel Kant Baltic Federal University · RUMoscow Regional Research Institute of Obstetrics and Gynecology · RURegional Clinical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial hypertension (AH) is a burning problem in the world. Antihypertensive pharmacological therapy combined by physical exercises is well-studied in patients with mild and moderate AH. However, studies that have investigated relaxation in patients with severe AH in addition to drug therapy are lacking. Optimization of a comprehensive treatment for patients with severe AH, by using a multicomponent rational antihypertensive pharmacotherapy (PT) with subsequent application of relaxation exercise therapy (RET). The study involved 32 male patients with severe AH. Initially, clinical-instrumental and laboratory examination, blood pressure registration and daily arterial blood pressure monitoring were carried out. Suitable PT was selected for all the patients. 3 months after starting PT the patients were divided in 2 groups. The patients of the 1st group were prescribed RET in addition to PT. The 2nd group of patients continued receiving PT alone. 3 months later, average daily blood pressure (ADBP)-syst and ADBP-diast were compared in both groups. Three months after PT both groups demonstrated a significant decrease in ADBP-syst and ADBP diast, but these indicators remained higher than normal and did not reach the target level. Three months after the inclusion of RET in the comprehensive treatment, the 1st group demonstrated a significant decrease in ADBP (systolic and diastolic), not only in comparison with the initial data, but also with the data observed three months after PT. After 6 months, ADBP-syst and ADBP-diast in the 1st group were significantly lower compared with those of patients in the 2nd group. The inclusion of RET in addition to a multicomponent antihypertensive PT is a promising treatment option for severe AH.

Identifiers

PMID34911289
PMCPMC8758959
OpenAlexW4200585265

What Socratic holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.