Evidence map›Paper›PMID 34916932›Full record

ArticleFrontiers in pharmacology2021

Ethnobotanical Survey on Skin Whitening Prescriptions of Traditional Chinese Medicine in Taiwan.

Chien-Yu Ko, Jung Chao, Pei-Yu Chen, Shan-Yu Su, Tomoji Maeda, Chin-Yu Lin, Hung-Che Chiang, Shyh-Shyun Huang

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Study of the Chemical Composition ofPlants (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chien-Yu KoSchool of Pharmacy, China Medical University, Taichung, Taiwan.
Jung ChaoChinese Medicine Research Center, Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, Master Program for Food and Drug Safety, China Medical University, Taichung, Taiwan.
Pei-Yu ChenDepartment of Cosmeceutics, China Medical University, Taichung, Taiwan.
Shan-Yu SuDepartment of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan.
Tomoji MaedaDepartment of Pharmaceutical Sciences, Nihon Pharmaceutical University, Saitama, Japan.
Chin-Yu LinTsuzuki Institute for Traditional Medicine, China Medical University, Taichung, Taiwan.
Hung-Che ChiangSchool of Pharmacy, China Medical University, Taichung, Taiwan.
Shyh-Shyun HuangSchool of Pharmacy, China Medical University, Taichung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing interest and demand for skin whitening products globally, particularly in Asia, have necessitated rapid advances in research on skin whitening products used in traditional Chinese medicine (TCM). Herein, we investigated 74 skin whitening prescriptions sold in TCM pharmacies in Taiwan. Commonly used medicinal materials were defined as those with a relative frequency of citation (RFC) > 0.2 and their characteristics were evaluated. Correlation analysis of commonly used medicinal materials was carried out to identify the core component of the medicinal materials. Of the purchased 74 skin whitening prescriptions, 36 were oral prescriptions, 37 were external prescriptions, and one prescription could be used as an oral or external prescription. After analysis, 90 traditional Chinese medicinal materials were obtained. The Apiaceae (10%; 13%) and Leguminosae (9%; 11%) were the main sources of oral and external medicinal materials, respectively. Oral skin whitening prescriptions were found to be mostly warm (46%) and sweet (53%), while external skin whitening prescriptions included cold (43%) and bitter (29%) medicinal materials. Additionally, mainly tonifying and replenishing effects of the materials were noted. Pharmacological analysis indicated that these medicinal materials may promote wound healing, treat inflammatory skin diseases, or anti-hyperpigmentation. According to the Spearman correlation analysis on interactions among medicinal materials with an RFC > 0.2 in the oral skin whitening prescriptions,

Indexed as

ethnobotanicalskin whiteningTaiwantraditional Chinese medicine pharmacytraditional Taiwanese medicine

Identifiers

PMID34916932
PMCPMC8670535

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.