Evidence map›Paper›PMID 34917519›Full record

ReviewFrontiers in cellular and infection microbiology2021

Oxidative Stress and Pathogenesis in Malaria.

Marilyn Vasquez, Marisol Zuniga, Ana Rodriguez

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 7 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 7 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Article
  10. Biological Activity ofInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Immunity beyond borders: non-lethalFrontiers in immunology · 2026
    Article
  18. Hepatorenal protective role of encapsulatedJournal of advanced veterinary and animal research · 2026
    Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marilyn VasquezDepartment of Microbiology, New York University Grossman School of Medicine, New York, NY, United States.
Marisol ZunigaDepartment of Microbiology, New York University Grossman School of Medicine, New York, NY, United States.
Ana RodriguezDepartment of Microbiology, New York University Grossman School of Medicine, New York, NY, United States.
New York University · US

Funding

Targeting the compromised brain endothelial barrier function during cerebral malaria with AT2 receptor agonistsR01HL150145 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RODRIGUEZ, ANA, STITT, ALAN · 2020 to 2023
$2.0M
Regulation of brain endothelial integrity by angiotensin receptors as treatment for cerebral malariaR01NS105910 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RODRIGUEZ, ANA, WALTHER, THOMAS · 2018 to 2022
$1.6M
Mechanisms of acute kidney injury in malaria - Resubmission - 1R21AI151349 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RODRIGUEZ, ANA · 2021 to 2022
$476k
NHLBI NIH HHS R01 HL150145NIAID NIH HHS R21 AI151349NINDS NIH HHS R01 NS105910
6 · The paper itself

Abstract

Malaria is a highly inflammatory and oxidative disease. The production of reactive oxygen species by host phagocytes is an essential component of the host response to

Indexed as

MalariaMalaria, FalciparumPlasmodiumErythrocytesHumansOxidative StressPlasmodium falciparumcerebral malariamalariaoxidationoxidative stresspathogenesisPlasmodium falciparumPlasmodium vivaxreactive oxygen species

Identifiers

PMID34917519
PMCPMC8669614
OpenAlexW3215363711

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.