Evidence mapPaperPMID 34922811Full record

ReviewJournal of diabetes and its complications2022

DCRM Multispecialty Practice Recommendations for the management of diabetes, cardiorenal, and metabolic diseases.

Yehuda Handelsman, John E Anderson, George L Bakris, Christie M Ballantyne, Joshua A Beckman, Deepak L Bhatt, Zachary T Bloomgarden, Biykem Bozkurt, Matthew J Budoff, Javed Butler and 21 more

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of diabetes and its complications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. The Role of Finerenone in Optimizing Cardiovascular-Kidney-Metabolic Health: Everything PCPs Should Know.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  12. Observational
  13. Review
  14. Review
  15. Cardio-renal-metabolic disease in primary care setting.Diabetes/metabolism research and reviews · 2024
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. SGLT2 Inhibitors vs. GLP-1 Agonists to Treat the Heart, the Kidneys and the Brain.Journal of cardiovascular development and disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 20 institutions in 2 countries.

Yehuda HandelsmanMetabolic Institute of America, Tarzana, CA, USA. Electronic address: yhandelsman@gmail.com.
John E AndersonThe Frist Clinic, Nashville, TN, USA.
George L BakrisUniversity of Chicago Medicine, Chicago, IL, USA.
Christie M BallantyneBaylor College of Medicine, Houston, TX, USA.
Joshua A BeckmanVanderbilt University Medical Center, Nashville, TN, USA.
Deepak L BhattBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Zachary T BloomgardenMount Sinai School of Medicine, New York, NY, USA.
Biykem BozkurtBaylor College of Medicine, Houston, TX, USA.
Matthew J BudoffDavid Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Javed ButlerUniversity of Mississippi Medical Center, Jackson, MS, USA.
Samuel Dagogo-JackUniversity of Tennessee Health Science Center, Memphis, TN, USA.
Ian H de BoerUniversity of Washington, Seattle, WA, USA.
Ralph A DeFronzoUniversity of Texas Health Science Center, San Antonio, TX, USA.
Robert H EckelUniversity of Colorado Anschutz Medical Campus, Denver, CO, USA.
Daniel EinhornScripps Whittier Institute for Diabetes, San Diego, CA, USA.
Vivian A FonsecaTulane University Health Sciences Center, New Orleans, LA, USA.
Jennifer B GreenDuke University Medical Center, Durham, NC, USA.
George GrunbergerGrunberger Diabetes Institute, Bloomfield Hills, MI, USA, Wayne State University School of Medicine, Detroit, MI, USA, Oakland University William Beaumont School of Medicine, Rochester, MI, USA, Charles University, Prague, Czech Republic.
Chris GuerinUniversity of California San Diego School of Medicine, San Diego, CA, USA.
Silvio E InzucchiYale School of Medicine, New Haven, CT, USA.
Paul S JellingerThe Center for Diabetes & Endocrine Care, University of Miami Miller School of Medicine, Hollywood, FL, USA.
Mikhail N KosiborodSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO, USA.
Pamela KushnerUniversity of California at Irvine, Irvine, CA, USA.
Norman LeporDavid Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Christian W MendeUniversity of California San Diego School of Medicine, San Diego, CA, USA.
Erin D MichosJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Jorge PlutzkyBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Pam R TaubUniversity of California San Diego School of Medicine, San Diego, CA, USA.
Guillermo E UmpierrezEmory University, Atlanta, GA, USA.
Muthiah VaduganathanBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Matthew R WeirUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Harvard University · USUniversity of California, San Diego · USBaylor College of Medicine · USUniversity of California, Los Angeles · USDuke Medical Center · USEmory University · USGrunberger Diabetes Institute · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins Medicine · USScripps Whittier Diabetes Institute · USTarzana Treatment Centers · USThe University of Texas Health Science Center at San Antonio · USTulane University · USUniversity of California, Irvine · USUniversity of Chicago · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Maryland, Baltimore · USUniversity of Miami · USUniversity of Mississippi Medical Center · USUniversity of Missouri–Kansas City · US

Funding

NIDDK NIH HHS R01 DK107239
6 · The paper itself

Abstract

Type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular disease (ASCVD), and heart failure (HF)-along with their associated risk factors-have overlapping etiologies, and two or more of these conditions frequently occur in the same patient. Many recent cardiovascular outcome trials (CVOTs) have demonstrated the benefits of agents originally developed to control T2D, ASCVD, or CKD risk factors, and these agents have transcended their primary indications to confer benefits across a range of conditions. This evolution in CVOT evidence calls for practice recommendations that are not constrained by a single discipline to help clinicians manage patients with complex conditions involving diabetes, cardiorenal, and/or metabolic (DCRM) diseases. The ultimate goal for these recommendations is to be comprehensive yet succinct and easy to follow by the nonexpert-whether a specialist or a primary care clinician. To meet this need, we formed a volunteer task force comprising leading cardiologists, nephrologists, endocrinologists, and primary care physicians to develop the DCRM Practice Recommendations, a multispecialty consensus on the comprehensive management of the patient with complicated metabolic disease. The task force recommendations are based on strong evidence and incorporate practical guidance that is clinically relevant and simple to implement, with the aim of improving outcomes in patients with DCRM. The recommendations are presented as 18 separate graphics covering lifestyle therapy, patient self-management education, technology for DCRM management, prediabetes, cognitive dysfunction, vaccinations, clinical tests, lipids, hypertension, anticoagulation and antiplatelet therapy, antihyperglycemic therapy, hypoglycemia, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), ASCVD, HF, CKD, and comorbid HF and CKD, as well as a graphical summary of medications used for DCRM.

Indexed as

Cardiovascular DiseasesCardiovascular SystemDiabetes Mellitus, Type 2Renal Insufficiency, ChronicHumansHypoglycemic AgentsHypoglycemic AgentsAtherosclerotic cardiovascular diseaseChronic kidney diseaseClinical practiceConsensus recommendationsHeart failureType 2 diabetes

Identifiers

PMID34922811
PMCPMC9803322
OpenAlexW4200095779

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.