Evidence map›Paper›PMID 34927464›Full record

ArticleJournal of the American Heart Association2022

Sex-Related Differences in Mortality Following Admission for Acute Heart Failure Across the Left Ventricular Ejection Fraction Spectrum.

Enrique Santas, Patricia Palau, Pau Llácer, Rafael de la Espriella, Gema Miñana, Gonzalo Núñez-Marín, Miguel Lorenzo, Raquel Heredia, Juan Sanchis, Francisco Javier Chorro and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Prognostic Clinical Phenotypes of Patients with Acute Decompensated Heart Failure.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Enrique SantasServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Patricia PalauServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Pau LlácerServicio de Medicina InternaHospital Universitario Ramón y Cajal Madrid Spain.
Rafael de la EspriellaServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Gema MiñanaServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Gonzalo Núñez-MarínServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.ORCID 0000-0003-2867-5344
Miguel LorenzoServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Raquel HerediaServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Juan SanchisServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.ORCID 0000-0003-0797-8709
Francisco Javier ChorroServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.
Antoni Bayés-GenísCIBERCV Madrid Spain.ORCID 0000-0002-3044-197X
Julio NúñezServicio de Cardiología Hospital Clínico UniversitarioUniversitat de ValènciaINCLIVA Valencia Spain.ORCID 0000-0003-1672-7119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Following a heart failure (HF)-decompensation, there is scarce data about sex-related prognostic differences across left ventricular ejection fraction (LVEF) status. We sought to evaluate sex-related differences in 6-month mortality risk across LVEF following admission for acute HF. Methods and Results We retrospectively evaluated 4812 patients consecutively admitted for acute HF in a multicenter registry from 3 hospitals. Study end points were all-cause, cardiovascular, and HF-related mortality at 6-month follow-up. Multivariable Cox regression models were fitted to investigate sex-related differences across LVEF. A total of 2243 (46.6%) patients were women, 2569 (53.4%) were men, and 2608 (54.2%) showed LVEF≥50%. At 6-month follow-up, 645 patients died (13.4%), being 544 (11.3%) and 416 (8.6%) cardiovascular and HF-related deaths, respectively. LVEF was not independently associated with mortality (HR, 1.02; 95% CI 0.99-1.05;

Indexed as

Heart FailureVentricular Function, LeftCause of DeathFemaleHumansMalePrognosisRetrospective StudiesStroke Volumeheart failureleft ventricular ejection fractionmortalitysex

Identifiers

PMID34927464
PMCPMC9075214

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.