Evidence map›Paper›PMID 34930299›Full record

Trial reportThe international journal of behavioral nutrition and physical activity2021

Contributions of changes in physical activity, sedentary time, diet and body weight to changes in cardiometabolic risk.

Eivind Andersen, Hidde P van der Ploeg, Willem van Mechelen, Cindy M Gray, Nanette Mutrie, Femke van Nassau, Judith G M Jelsma, Annie S Anderson, Marlene N Silva, Hugo V Pereira and 8 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The international journal of behavioral nutrition and physical activity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 4 countries.

Eivind AndersenInstitute for Sport and Social Science, Norwegian School of Sport Science, PO box 4014, Ullevål stadium, 0806, Oslo, Norway. Eivind.andersen@usn.no.
Hidde P van der PloegAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam, the Netherlands.
Willem van MechelenAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam, the Netherlands.
Cindy M GrayInstitute of Health and Wellbeing, College of Social Sciences, University of Glasgow, Glasgow, UK.
Nanette MutriePhysical Activity for Health Research Centre, the University of Edinburgh, Edinburgh, UK.
Femke van NassauAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam, the Netherlands.
Judith G M JelsmaAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam, the Netherlands.
Annie S AndersonCentre for Public Health Nutrition Research, University of Dundee, Dundee, UK.
Marlene N SilvaCIDEFES, Faculdade de Educação Física e Desporto, Universidade Lusófona, Lisboa, Portugal.
Hugo V PereiraCIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, Lisboa, Portugal.
Alex McConnachieRobertson Centre for Biostatistics, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Naveed SattarInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Marit SørensenInstitute for Sport and Social Science, Norwegian School of Sport Science, PO box 4014, Ullevål stadium, 0806, Oslo, Norway.
Øystein B RøynesdalInstitute for Sport and Social Science, Norwegian School of Sport Science, PO box 4014, Ullevål stadium, 0806, Oslo, Norway.
Kate HuntInstitute for Social Marketing and Health, University of Stirling, Stirling, UK.
Glyn C RobertsInstitute for Sport and Social Science, Norwegian School of Sport Science, PO box 4014, Ullevål stadium, 0806, Oslo, Norway.
Sally WykeInstitute of Health and Wellbeing, College of Social Sciences, University of Glasgow, Glasgow, UK.
Jason M R GillInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
University of Glasgow · GBNorwegian School of Sport Sciences · NOVrije Universiteit Amsterdam · NLAmsterdam University Medical Centers · NLUniversidade Lusófona · PTUniversity of Dundee · GBUniversity of Edinburgh · GBUniversity of Lisbon · PTUniversity of Stirling · GB

Funding

Medical Research Council MC_UU_12017/12
6 · The paper itself

Abstract

backgroundIncreased physical activity (PA), reduced time spent sedentary (SED), healthier diet and reduced body weight may all have a positive impact on cardiometabolic risk. The relative importance of change in each of these variables on cardiometabolic risk, however, is unclear. We therefore sought to investigate the relative contributions of changes in PA, SED, diet and body weight on cardiometabolic risk.

methodsThis is a secondary analysis of data collected from the EuroFIT randomised controlled trial, which was a 12-week group-based lifestyle intervention for overweight middle-aged men delivered by coaches in football club stadia aiming to improve PA, SED, diet, and body weight. PA and SED were assessed by accelerometry, diet using the Dietary Instrument for Nutrition Education (DINE). An overall cardiometabolic risk score was derived from combining z-scores for glucose, HbA1c, insulin, lipids and blood pressure. In total, 707 men (from the overall cohort of 1113) with complete data for these variables at baseline and 12-month follow-up were included in the multivariable linear regression analyses.

resultsIn multivariable analyses, change in number of steps (explaining 5.1% of R

conclusionChange in body weight, together with baseline cardiometabolic risk explained most of the change in cardiometabolic risk. Thus, the benefits of increasing physical activity and improving diet on cardiometabolic risk appear to act largely via an effect on changes in body weight.

trial registrationInternational Standard Randomised Controlled Trials, ISRCTN-81935608. Registered 06052015. https://www.isrctn.com/ISRCTN81935608?q=&filters=recruitmentCountry:Portugal&sort=&offset=7&totalResults=92&page=1&pageSize=10&searchType=basic-search.

Indexed as

Cardiovascular DiseasesSedentary BehaviorDietExerciseHumansMaleMiddle AgedOverweightbody weightCardiovascular healthphysical activitysedentary time

Identifiers

PMID34930299
PMCPMC8686269
OpenAlexW4200585139

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.