Evidence map›Paper›PMID 34940903›Full record

ArticleHNO2022

High prevalence of long-term olfactory dysfunction confirmed by olfactory testing after a community COVID-19 outbreak.

Hilmar Gudziol, Timo Kirschstein, Mathias W Pletz, Sebastian Weis, Orlando Guntinas-Lichius, Thomas Bitter, CoNAN study group

Open access · hybridAbstract read
In one paragraph

Article in HNO, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hilmar GudziolDepartment of Otorhinolaryngology, Jena University Hospital, Friedrich Schiller University, Am Klinikum 1, 07740, Jena, Germany.
Timo KirschsteinDepartment of Otorhinolaryngology, Jena University Hospital, Friedrich Schiller University, Am Klinikum 1, 07740, Jena, Germany.
Mathias W PletzInstitute for Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Sebastian WeisInstitute for Infectious Diseases and Infection Control, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Orlando Guntinas-LichiusDepartment of Otorhinolaryngology, Jena University Hospital, Friedrich Schiller University, Am Klinikum 1, 07740, Jena, Germany. orlando.guntinas@med.uni-jena.de.ORCID http://orcid.org/0000-0001-9671-0784
Thomas BitterDepartment of Otorhinolaryngology, Jena University Hospital, Friedrich Schiller University, Am Klinikum 1, 07740, Jena, Germany.
CoNAN study group
Jena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe prevalence of long-term olfactory and gustatory dysfunction in participants suffering from sudden chemosensory loss due to coronavirus disease 2019 (COVID-19) is unknown. Furthermore, evaluations of the reliability of participants' self-reporting of olfactory function (SOF) and gustatory function (SGF) using extended objective psychophysical testing are missing.

methodsIn this population-based cohort study in a PCR-tested community in Thuringia, Germany, olfactory function was extensively examined 4 months after a COVID-19 outbreak using the "Sniffin Sticks" test battery to determine the TDI

resultsOf 43 adult convalescents (median age: 68 years; 58% female) after SARS-CoV‑2 infection, 18 participants (42%) had olfactory complaints due to SOF, one participant (2%) complained of taste disturbance due to SGF. The TDI

conclusionThe SOF was reliable, especially for participants who felt a sudden chemosensory dysfunction during the outbreak. At 4 months after SARS-CoV‑2 infection, a high proportion of participants were dysosmic, whereas nearly all of them had normal taste function.

Indexed as

COVID-19Olfaction DisordersAdultAgedCohort StudiesDisease OutbreaksFemaleHumansMalePrevalenceReproducibility of ResultsSARS-CoV-2SmellCoronavirusLong-term sequelaeOlfactionOutbreakSmell

Identifiers

PMID34940903
PMCPMC8697538
OpenAlexW4200434917

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.