Evidence map›Paper›PMID 34941776›Full record

ArticleToxics2021

Alterations in CNS Functions and DNA Methylation in Rats after 24 h Exposure to Peat Smoke.

Vera A Vokina, Larisa M Sosedova, Mikhail A Novikov, Viktor S Rukavishnikov, Ekaterina A Kapustina, Anton N Alekseenko, Elizaveta S Andreeva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vera A VokinaFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.ORCID 0000-0002-8165-8052
Larisa M SosedovaFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.
Mikhail A NovikovFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.ORCID 0000-0002-6100-6292
Viktor S RukavishnikovFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.
Ekaterina A KapustinaFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.
Anton N AlekseenkoFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.
Elizaveta S AndreevaFSBSI East-Siberian Institute of Medical and Ecological Research, 665827 Angarsk, Russia.

Funding

Ministry of Science and Higher Education 075-15-2020-787
6 · The paper itself

Abstract

The use of a developed experimental model of a natural fire made it possible to assess the consequences of 24 h exposure to peat combustion products in albino rats. Peat smoke exposure leads to behavioral disturbances in rats, characterized by an increase in locomotor activity and an increased level of anxiety. Indicators of brain bioelectrical activity of the exposed animals supported the state of anxiety and psychoemotional stress. Epigenetic changes in the blood cells of exposed animals were revealed under 24 h exposure to peat smoke, characterized by a decrease in the level of global DNA methylation.

Indexed as

behaviorDNA fragmentation and methylationEEGpeat smokerats

Identifiers

PMID34941776
PMCPMC8709141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.