Evidence map›Paper›PMID 34943131›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Long-Term Effects of Biliverdin Reductase a Deficiency in

Giulia Bortolussi, Xiaoxia Shi, Lysbeth Ten Bloemendaal, Bhaswati Banerjee, Dirk R De Waart, Gabriele Baj, Weiyu Chen, Ronald P Oude Elferink, Ulrich Beuers, Coen C Paulusma and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Self-powered, light-controlled, bioresorbable platforms for programmed drug delivery.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Bilirubin 2022: The Past, the Present and the Future.Antioxidants (Basel, Switzerland) · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Giulia BortolussiInternational Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.
Xiaoxia ShiTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Lysbeth Ten BloemendaalTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Bhaswati BanerjeeInternational Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.ORCID 0000-0003-2231-7263
Dirk R De WaartTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Gabriele BajLight Microscopy Imaging Center, Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-2625-9454
Weiyu ChenHeart Research Institute, Sydney, NSW 2042, Australia.
Ronald P Oude ElferinkTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Ulrich BeuersTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Coen C PaulusmaTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Roland StockerHeart Research Institute, Sydney, NSW 2042, Australia.
Andrés F MuroInternational Centre for Genetic Engineering and Biotechnology, 34149 Trieste, Italy.ORCID 0000-0002-9628-0494
Piter J BosmaTytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLInternational Centre for Genetic Engineering and Biotechnology · ITThe Heart Research Institute · AUDalian University of Technology · CNUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulation of neurotoxic bilirubin due to a transient neonatal or persistent inherited deficiency of bilirubin glucuronidation activity can cause irreversible brain damage and death. Strategies to inhibit bilirubin production and prevent neurotoxicity in neonatal and adult settings seem promising. We evaluated the impact of

Indexed as

agingCrigler-NajjarfetusGilbertiron accumulationPrdx2triglycerides

Identifiers

PMID34943131
PMCPMC8698966
OpenAlexW4200424339

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.