Evidence map›Paper›PMID 34943907›Full record

ArticleCells2021

Overexpression of Neuroglobin Promotes Energy Metabolism and Autophagy Induction in Human Neuroblastoma SH-SY5Y Cells.

Valeria Manganelli, Illari Salvatori, Michele Costanzo, Antonella Capozzi, Daniela Caissutti, Marianna Caterino, Cristiana Valle, Alberto Ferri, Maurizio Sorice, Margherita Ruoppolo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Proteomics and Metabolomics in Biomedicine.International journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Deciphering the Relationship between SARS-CoV-2 and Cancer.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. COVIDomics: The Proteomic and Metabolomic Signatures of COVID-19.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Valeria ManganelliDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Illari SalvatoriFondazione Santa Lucia IRCCS, c/o CERC, 00143 Rome, Italy.
Michele CostanzoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-6386-2009
Antonella CapozziDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Daniela CaissuttiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Marianna CaterinoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-6035-8213
Cristiana ValleFondazione Santa Lucia IRCCS, c/o CERC, 00143 Rome, Italy.ORCID 0000-0002-0914-6511
Alberto FerriFondazione Santa Lucia IRCCS, c/o CERC, 00143 Rome, Italy.ORCID 0000-0002-4097-0605
Maurizio SoriceDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Margherita RuoppoloDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-7364-0602
Tina GarofaloDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0645-2510
Roberta MisasiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Sapienza University of Rome · ITCeinge Biotecnologie Avanzate (Italy) · ITFondazione Santa Lucia · IT

Funding

Ministry of Education, Universities and Research PRIN 2017 FS5SHLMinistry of Education, Universities and Research PRIN 2017 SNRXH3
6 · The paper itself

Abstract

Neuroglobin (NGB) is an O

Indexed as

Adenosine TriphosphateAutophagyCell Line, TumorEnergy MetabolismGene Expression Regulation, NeoplasticHumansMicrotubule-Associated ProteinsMitochondriaNeuroblastomaNeuroglobinOxygen ConsumptionProteomeSequestosome-1 ProteinAdenosine TriphosphateMAP1LC3B protein, humanMicrotubule-Associated ProteinsNeuroglobinProteomeSequestosome-1 ProteinSQSTM1 protein, humanautophagyenergy metabolismlabel-free proteomicsmitochondrianeuroglobinSH-SY5Y neuroblastoma cells

Identifiers

PMID34943907
PMCPMC8699457
OpenAlexW3217365406

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.