Evidence map›Paper›PMID 34943913›Full record

ReviewCells2021

Impact of Pharmacological and Non-Pharmacological Modulators on Dendritic Spines Structure and Functions in Brain.

Arehally M Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Tousif Ahmed Hediyal, Praveen Raj, Annan Gopinath Rathipriya, M Walid Qoronfleh, Musthafa Mohamed Essa, Saravana Babu Chidambaram

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Signal mining and risk analysis of olanzapine adverse events in the FAERS database.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025
    Article
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Arehally M MahalakshmiDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.
Bipul RayDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.
Sunanda TuladharDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.
Tousif Ahmed HediyalDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.
Praveen RajDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.
Annan Gopinath RathipriyaFood and Brain Research Foundation, Chennai 600094, Tamil Nadu, India.
M Walid QoronflehQ3CG Research Institute (QRI), Research and Policy Division, 7227 Rachel Drive, Ypsilanti, MI 48917, USA.ORCID 0000-0001-6757-1922
Musthafa Mohamed EssaDepartment of Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat 123, Oman.
Saravana Babu ChidambaramDepartment of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570015, Karnataka, India.ORCID 0000-0003-2357-056X
JSS Academy of Higher Education and Research · INIndia Diabetes Research Foundation · INUniversity of the Pacific · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic spines are small, thin, hair-like protrusions found on the dendritic processes of neurons. They serve as independent compartments providing large amplitudes of Ca

Indexed as

DietCholinergic AgentsCognitive DysfunctionDendritic SpinesExcitatory Amino Acid AgentsGABA AgentsHumansMeditationNeurodegenerative DiseasesNeuronsSynapsesYogaCholinergic AgentsExcitatory Amino Acid AgentsGABA Agentsdendritic spinesdietenriched environmentmodulatorspharmacological modulatorsyoga and meditation

Identifiers

PMID34943913
PMCPMC8699406
OpenAlexW3217629825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.