Evidence map›Paper›PMID 34943983›Full record

ArticleCells2021

Long-Term Treatment with Atypical Antipsychotic Iloperidone Modulates Cytochrome P450 2D (CYP2D) Expression and Activity in the Liver and Brain via Different Mechanisms.

Przemysław J Danek, Władysława A Daniel

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Neurosteroid influence on affective tone.Neuroscience and biobehavioral reviews · 2023
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Przemysław J DanekDepartment of Pharmacokinetics and Drug Metabolism, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.ORCID 0000-0002-7137-2990
Władysława A DanielDepartment of Pharmacokinetics and Drug Metabolism, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, 31-343 Kraków, Poland.ORCID 0000-0002-1226-1721
Maj Institute of Pharmacology · PL

Funding

National Science Center Preludium 16 no 2018/31/N/NZ/01857
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntipsychotic AgentsBrainCytochrome P-450 Enzyme SystemDisease Models, AnimalGene Expression Regulation, NeoplasticHumansIsoxazolesLiverPiperidinesRatsRats, WistarSchizophreniaSubstantia NigraAntipsychotic AgentsCytochrome P-450 Enzyme SystemiloperidoneIsoxazolesPiperidinesbraincytochrome P450 2D expression/activityiloperidoneliverprolonged administration

Identifiers

PMID34943983
PMCPMC8700221
OpenAlexW4200371405

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.