ArticleMicromachines2021
Osmotically Enabled Wearable Patch for Sweat Harvesting and Lactate Quantification.
Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Smart patches for healthcare industry: a review of emerging technologies, challenges, and developmental opportunities.Biomedical engineering online · 2026Review
- A Granular Hydrogel-Enabled Wearable Electrochemical Biosensing Platform for Continuous Non-Invasive Sweat Lactate Detection.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Skin-Interfaced Wearable Sweat Sensors for Precision Medicine.Chemical reviews · 2023Review
- Technology Roadmap for Flexible Sensors.ACS nano · 2023Review
- Implications of the Onset of Sweating on the Sweat Lactate Threshold.Sensors (Basel, Switzerland) · 2023Article
- Epidermal Wearable Biosensors for Monitoring Biomarkers of Chronic Disease in Sweat.Biosensors · 2023Review
- Recent Advances in Wearable Biosensors for Non-Invasive Detection of Human Lactate.Biosensors · 2022Review
- Editorial for the Special Issue on Micro/Nanofluidic and Lab-on-a-Chip Devices for Biomedical Applications.Micromachines · 2022Article
- A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices.Sensors (Basel, Switzerland) · 2022Review
- A One-Dollar, Disposable, Paper-Based Microfluidic Chip for Real-Time Monitoring of Sweat Rate.Micromachines · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Lactate is an essential biomarker for determining the health of the muscles and oxidative stress levels in the human body. However, most of the currently available sweat lactate monitoring devices require external power, cannot measure lactate under low sweat rates (such as in humans at rest), and do not provide adequate information about the relationship between sweat and blood lactate levels. Here, we discuss the on-skin operation of our recently developed wearable sweat sampling patch. The patch combines osmosis (using hydrogel discs) and capillary action (using paper microfluidic channel) for long-term sweat withdrawal and management. When subjects are at rest, the hydrogel disc can withdraw fluid from the skin via osmosis and deliver it to the paper. The lactate amount in the fluid is determined using a colorimetric assay. During active sweating (e.g., exercise), the paper can harvest sweat even in the absence of the hydrogel patch. The captured fluid contains lactate, which we quantify using a colorimetric assay. The measurements show the that the total number of moles of lactate in sweat is correlated to sweat rate. Lactate concentrations in sweat and blood correlate well only during high-intensity exercise. Hence, sweat appears to be a suitable biofluid for lactate quantification. Overall, this wearable patch holds the potential of providing a comprehensive analysis of sweat lactate trends in the human body.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.