Evidence map›Paper›PMID 34947679›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Novel Perspectives towards RNA-Based Nano-Theranostic Approaches for Cancer Management.

Rabia Arshad, Iqra Fatima, Saman Sargazi, Abbas Rahdar, Milad Karamzadeh-Jahromi, Sadanand Pandey, Ana M Díez-Pascual, Muhammad Bilal

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
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  9. Advances in nanomedicine and delivery systems for gastric cancer research.Frontiers in bioengineering and biotechnology · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Nanomaterials for Drug Delivery and Cancer Therapy.Nanomaterials (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rabia ArshadFaculty of Pharmacy, University of Lahore, Lahore 45320, Pakistan.ORCID 0000-0001-7654-3456
Iqra FatimaDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Saman SargaziCellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan 98167-43463, Iran.ORCID 0000-0002-2255-5977
Abbas RahdarDepartment of Physics, University of Zabol, Zabol 98613-35856, Iran.ORCID 0000-0003-4766-9214
Milad Karamzadeh-JahromiDepartment of Physics, University of Kashan, Kashan 87317-51167, Iran.
Sadanand PandeyDepartment of Chemistry, College of Natural Science, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Korea.ORCID 0000-0003-2065-897X
Ana M Díez-PascualUniversidad de Alcalá, Facultad de Ciencias, Departamento de Química Analítica, Química Física e Ingeniería Química, Ctra. Madrid-Barcelona, Km. 33.6, 28805 Alcalá de Henares, Madrid, Spain.ORCID 0000-0001-7405-2354
Muhammad BilalSchool of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an 223003, China.ORCID 0000-0001-5388-3183

Funding

Comunidad de Madrid EPU-INV/2020/012
6 · The paper itself

Abstract

In the fight against cancer, early diagnosis is critical for effective treatment. Traditional cancer diagnostic technologies, on the other hand, have limitations that make early detection difficult. Therefore, multi-functionalized nanoparticles (NPs) and nano-biosensors have revolutionized the era of cancer diagnosis and treatment for targeted action via attaching specified and biocompatible ligands to target the tissues, which are highly over-expressed in certain types of cancers. Advancements in multi-functionalized NPs can be achieved via modifying molecular genetics to develop personalized and targeted treatments based on RNA interference. Modification in RNA therapies utilized small RNA subunits in the form of small interfering RNAs (siRNA) for overexpressing the specific genes of, most commonly, breast, colon, gastric, cervical, and hepatocellular cancer. RNA-conjugated nanomaterials appear to be the gold standard for preventing various malignant tumors through focused diagnosis and delivering to a specific tissue, resulting in cancer cells going into programmed death. The latest advances in RNA nanotechnology applications for cancer diagnosis and treatment are summarized in this review.

Indexed as

cancernano-biosensorRNA nanotechnologytheranostic

Identifiers

PMID34947679
PMCPMC8708502

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.