Evidence map›Paper›PMID 34948814›Full record

ArticleInternational journal of environmental research and public health2021

Severe COVID-19 Complicated by Cerebral Venous Thrombosis in a Newborn Successfully Treated with Remdesivir, Glucocorticoids, and Hyperimmune Plasma.

Laura Cursi, Francesca Ippolita Calo Carducci, Sara Chiurchiu, Lorenza Romani, Francesca Stoppa, Giulia Lucignani, Cristina Russo, Daniela Longo, Carlo Federico Perno, Corrado Cecchetti and 5 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Laura CursiAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Francesca Ippolita Calo CarducciAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Sara ChiurchiuAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Lorenza RomaniAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Francesca StoppaDepartment of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Giulia LucignaniImaging Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Cristina RussoDepartment of Laboratories, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Daniela LongoImaging Department, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Carlo Federico PernoDepartment of Laboratories, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Corrado CecchettiDepartment of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Mary Haywood LombardiDepartment of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Patrizia D'ArgenioAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Laura LancellaAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Stefania BernardiAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Paolo RossiAcademic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic, affecting all age groups with a wide spectrum of clinical presentation ranging from asymptomatic to severe interstitial pneumonia, hyperinflammation, and death. Children and infants generally show a mild course of the disease, although infants have been observed to have a higher risk of hospitalization and severe outcomes. Here, we report the case of a preterm infant with a severe form of SARS-CoV-2 infection complicated by cerebral venous thrombosis successfully treated with steroids, hyperimmune plasma, and remdesivir.

Indexed as

COVID-19 Drug TreatmentVenous ThrombosisAdenosine MonophosphateAlanineChildGlucocorticoidsHumansInfantInfant, NewbornInfant, PrematureSARS-CoV-2Adenosine MonophosphateAlanineGlucocorticoidsremdesivircerebral thrombosisCOVID-19newbornremdesivirSARS-CoV-2

Identifiers

PMID34948814
PMCPMC8701660
OpenAlexW4200602217

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.