Evidence map›Paper›PMID 34956233›Full record

ReviewFrontiers in immunology2021

Metabolic Adaptations During

Kara R Eichelberger, James E Cassat

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 57 citations in OpenAlex.

  1. Virulence · 2026
    Article
  2. Mesolens imaging in microbiology.Essays in biochemistry · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Copper-driven mutualism ofMicrobiology (Reading, England) · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Antibiotics (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Current research in microbial sciences · 2024
    Article
  18. Time-lapse mesoscopy ofMicrobiology (Reading, England) · 2024
    Article
  19. Article
  20. Candida-bacterial cross-kingdom interactions.Trends in microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kara R EichelbergerDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States.
James E CassatDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States.
Vanderbilt University Medical Center · US

Funding

Childhood Infections Research ProgramT32AI095202 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JAMES E CASSAT · 2011 to 2026
$4.2M
Defining the impact of host factors on the molecular architecture and bacterial physiology of Staphylococcus aureus abscessesR01AI145992 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E, SKAAR, ERIC P · 2020 to 2024
$3.8M
Differential Inflammasome Regulation in the pathogenesis of S. aureus osteomyelitisR01AI161022 · NIAID · WASHINGTON UNIVERSITY · PI CASSAT, JAMES E, MBALAVIELE, GABRIEL · 2021 to 2025
$3.4M
The impact of hypoxia on Staphylococcus aureus metabolism and virulence during osteomyelitisR01AI132560 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI132560NIAID NIH HHS R01 AI145992NIAID NIH HHS R01 AI161022NIAID NIH HHS T32 AI095202
6 · The paper itself

Abstract

Successful pathogens require metabolic flexibility to adapt to diverse host niches. The presence of co-infecting or commensal microorganisms at a given infection site can further influence the metabolic processes required for a pathogen to cause disease. The Gram-positive bacterium

Indexed as

Adaptation, PhysiologicalAnimalsBiofilmsCandida albicansCandidiasisCoinfectionHumansMicrobial InteractionsStaphylococcal InfectionsStaphylococcus aureusCandida albicansfungal-bacterial interactionspolymicrobial biofilmpolymicrobial infectionStaphylococcus aureus

Identifiers

PMID34956233
PMCPMC8692374
OpenAlexW4200157502

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.