Evidence map›Paper›PMID 34956563›Full record

ArticleJournal of healthcare engineering2021

CircRNA RERE Promotes the Oxidative Stress-Induced Apoptosis and Autophagy of Nucleus Pulposus Cells through the miR-299-5p/Galectin-3 Axis.

Rong Wang, Xingchao Zhou, Guorui Luo, Jin Zhang, Min Yang, Chao Song

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. AAGGG repeat expansions triggerScience advances · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rong WangDepartment of Rehabilitation Medicine, Anningshi First People's Hospital, 2 Henan Road, 650302 Anning, Yunnan, China.
Xingchao ZhouEquipment Department, The First Affiliated Hospital of Dali University, 32 Jiashibai Road, 671000 Dali, Yunnan, China.
Guorui LuoDepartment of Rehabilitation Medicine, Anningshi First People's Hospital, 2 Henan Road, 650302 Anning, Yunnan, China.
Jin ZhangDepartment of Rehabilitation Medicine, Anningshi First People's Hospital, 2 Henan Road, 650302 Anning, Yunnan, China.
Min YangDepartment of Rehabilitation Medicine, Anningshi First People's Hospital, 2 Henan Road, 650302 Anning, Yunnan, China.
Chao SongPain Management, Anningshi First People's Hospital, 2 Henan Road, 650302 Anning, Yunnan, China.ORCID 0000-0002-3066-3425
Dali University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intervertebral disc degeneration (IDD) is widely accepted as a cause of low back pain and related degenerative musculoskeletal disorders. Nucleus pulposus (NP) cell loss is closely related to IDD progression. Thus, investigating the specifically targeted therapeutic agents against NP cell loss depends on understanding the molecular mechanisms. In this study, human NP cells were treated with hydrogen peroxide (H

Indexed as

Galectin 3MicroRNAsNucleus PulposusRNA, CircularApoptosisAutophagyCarrier ProteinsHumansHydrogen PeroxideOxidative StressCarrier ProteinsGalectin 3Hydrogen PeroxideMicroRNAsMIRN299 microRNA, humanRERE protein, humanRNA, Circular

Identifiers

PMID34956563
PMCPMC8695020
OpenAlexW4200124643

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.