Evidence map›Paper›PMID 34956579›Full record

ArticleJournal of healthcare engineering2021

Correlation between Changes in Serum RBP4, hs-CRP, and IL-27 Levels and Rosuvastatin in the Treatment of Coronary Heart Disease.

Yali Wang, Changrui Zhou, Tianlian Yu, Feng Zhao

Open access · hybridAbstract read
In one paragraph

Article in Journal of healthcare engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Recent Insights Into Targeting Interleukin-27 in Coronary Artery Disease.Journal of cardiovascular translational research · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yali WangDepartment of Internal Medicine-Cardiovascular, Dongying Traditional Chinese Medicine Hospital, Dongying 257055, Shandong Province, China.
Changrui ZhouDepartment of Clinical Laboratory, Dongying Traditional Chinese Medicine Hospital, Dongying 257055, Shandong Province, China.
Tianlian YuDepartment of Clinical Laboratory, Dongying Traditional Chinese Medicine Hospital, Dongying 257055, Shandong Province, China.
Feng ZhaoDepartment of Internal Medicine-Cardiovascular, Dongying Traditional Chinese Medicine Hospital, Dongying 257055, Shandong Province, China.ORCID 0000-0003-2690-5302
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the correlation between changes in serum RBP4, hs-CRP, and IL-27 levels and rosuvastatin in the treatment of coronary heart disease (CHD).

methodsOne hundred and twenty patients with CHD admitted in our hospital were selected as the research object, including 60 patients with acute coronary syndrome as the ACS group, and 60 patients with stable angina as the SA group. Another 60 patients without CHD who were examined in our hospital at the same time were included in the non-CHD group. The patients with CHD were further divided into the control group (CG) (

resultsAfter retrospective analysis, no significant difference was found among the ACS group, the SA group, and the non-CHD group (

conclusionSerum RBP4, hs-CRP, and IL-27 play an important role in the occurrence and development of CHD, with a positive correlation to the Gensini score, which can indicate the severity of cardiovascular disease to a certain extent. Meanwhile, rosuvastatin can remarkably reduce serum RBP4, hs-CRP, and IL-27 levels, which is of significance for prognosis.

Indexed as

Coronary DiseaseInterleukin-27C-Reactive ProteinHumansRetinol-Binding Proteins, PlasmaRetrospective StudiesRosuvastatin CalciumC-Reactive ProteinInterleukin-27RBP4 protein, humanRetinol-Binding Proteins, PlasmaRosuvastatin Calcium

Identifiers

PMID34956579
PMCPMC8695037
OpenAlexW4200031593

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.