ArticleJournal of Alzheimer's disease : JAD2022
Association Between Motor Task Performance and Hippocampal Atrophy Across Cognitively Unimpaired, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease Individuals.
Article in Journal of Alzheimer's disease : JAD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Average performance and performance variability on a brief functional fine motor test reflect distinct behavioral constructs in aging.Frontiers in aging neuroscience · 2026Article
- Comparing Demographic Effects on Current and Novel Neuropsychological Measures in Older Adults with and without Alzheimer's Disease.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Article
- Validating a brief performance-based measure of cognition and daily functioning in amnestic mild cognitive impairment and mild Alzheimer's disease.Journal of Alzheimer's disease : JAD · 2025Article
- Neural Underpinnings of Learning in Dementia Populations: A Review of Motor Learning Studies Combined with Neuroimaging.Journal of cognitive neuroscience · 2024Review
- Classification of Mild Cognitive Impairment and Alzheimer's Disease Using Manual Motor Measures.Neuro-degenerative diseases · 2024Article
- Examining the Diagnostic Accuracy of a Novel Performance-Based Test for Alzheimer's Disease Screening.The journal of prevention of Alzheimer's disease · 2024Article
- Age and sex effects on Super G performance are consistent across internet devices.International journal of serious games · 2023Article
- Volumetric regional MRI and neuropsychological predictors of motor task variability in cognitively unimpaired, Mild Cognitive Impairment, and probable Alzheimer's disease older adults.Experimental gerontology · 2023Article
- Rey-Osterrieth complex figure recall scores and motor skill learning in older adults: A non-linear mixed effect model-based analysis.Human movement science · 2022Article
- Article
- Remote, Unsupervised Functional Motor Task Evaluation in Older Adults across the United States Using the MindCrowd Electronic Cohort.Developmental neuropsychology · 2021Article
- Cortical Thickness Predictors of Performance-Based Functional Task Variability in the Alzheimer Disease Spectrum.Alzheimer disease and associated disordersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Hippocampal atrophy is a widely used biomarker for Alzheimer's disease (AD), but the cost, time, and contraindications associated with magnetic resonance imaging (MRI) limit its use. Recent work has shown that a low-cost upper extremity motor task has potential in identifying AD risk. Fifty-four older adults (15 cognitively unimpaired, 24 amnestic mild cognitive impairment, and 15 AD) completed six motor task trials and a structural MRI. Several measures of motor task performance significantly predicted bilateral hippocampal volume, controlling for age, sex, education, and memory. Thus, this motor task may be an affordable, non-invasive screen for AD risk and progression.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.