Evidence map›Paper›PMID 34959439›Full record

ArticlePharmaceutics2021

Formulation of Lipid-Based Tableted Spray-Congealed Microparticles for Sustained Release of Vildagliptin: In Vitro and In Vivo Studies.

Khaled H Al Zahabi, Hind Ben Tkhayat, Ehab Abu-Basha, Al Sayed Sallam, Husam M Younes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khaled H Al ZahabiTissue Engineering & Nanopharmaceuticals Research Laboratory, Qatar University, Doha P.O. Box 2713, Qatar.
Hind Ben TkhayatTissue Engineering & Nanopharmaceuticals Research Laboratory, Qatar University, Doha P.O. Box 2713, Qatar.
Ehab Abu-BashaDepartment of Veterinary Basic Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Al Sayed SallamAl-Taqaddom Pharmaceutical Industries, Amman 11947, Jordan.ORCID 0000-0002-7872-2084
Husam M YounesTissue Engineering & Nanopharmaceuticals Research Laboratory, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0002-8191-4415

Funding

Qatar National Research Fund NPRP13S-0126-200173
6 · The paper itself

Abstract

Spray-congealing (SPC) technology was utilized to prepare lipid-based microparticles (MP) capable of sustaining the release of Vildagliptin (VG) for use as a once-daily treatment for type 2 diabetes mellitus. VG microparticles were prepared using Compritol

Indexed as

bioavailability studyin vitro–in vivo correlationlipid excipientspharmacokineticsspray congealingsustained-releasetype-2 diabetesvildagliptin

Identifiers

PMID34959439
PMCPMC8709051

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.