Evidence map›Paper›PMID 34959636›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

The Effect of Curcumin Differs on Individual Cognitive Domains across Different Patient Populations: A Systematic Review and Meta-Analysis.

I-Chen Tsai, Chih-Wei Hsu, Chun-Hung Chang, Ping-Tao Tseng, Ke-Vin Chang

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 7 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 7 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

I-Chen TsaiInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-4356-918X
Chih-Wei HsuDepartment of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.ORCID 0000-0002-8650-4060
Chun-Hung ChangInstitute of Clinical Medical Science, China Medical University, Taichung 404333, Taiwan.ORCID 0000-0003-2949-5855
Ping-Tao TsengProspect Clinic for Otorhinolaryngology & Neurology, Kaohsiung 811022, Taiwan.ORCID 0000-0001-5761-7800
Ke-Vin ChangDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10048, Taiwan.ORCID 0000-0002-7558-5651
Chang Gung University · TWChina Medical University · TWNational Sun Yat-sen University · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology Taiwan 106-2314-B-002-180-MY3Ministry of Science and Technology Taiwan 109-2314-B-002-114-MY3
6 · The paper itself

Abstract

Curcumin is a polyphenol with strong antioxidant and anti-inflammatory effects that has been shown to be effective in ameliorating cognitive decline in animal studies. However, its clinical effectiveness is inconclusive, and relevant gastrointestinal adverse events (AEs) have been reported. The aim of this meta-analysis was to summarize the existing evidence from randomized controlled trials (RCTs) of effects of curcumin on overall cognitive function, individual cognitive domains, and gastrointestinal AE. The study includes 8 RCTs and 389 participants. A random-effects model was used for the meta-analysis. Compared with the placebo group, the curcumin group was associated with an improvement in working memory (Hedges'

Indexed as

cognitioncognitive functionCurcuma longacurcuminturmeric

Identifiers

PMID34959636
PMCPMC8708668
OpenAlexW3201916136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.