Evidence map›Paper›PMID 34959664›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Medical-Grade Honey Outperforms Conventional Treatments for Healing Cold Sores-A Clinical Study.

Piyu Parth Naik, Dimitris Mossialos, Bas van Wijk, Petra Novakova, Frank A D T G Wagener, Niels A J Cremers

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Piyu Parth NaikSaudi German Hospitals and Clinics, Department of Dermatology, Hessa Street 331 West, Al Barsha 3, Exit 36 Sheikh Zayed Road, Dubai P.O. Box 391093, United Arab Emirates.ORCID 0000-0002-6499-4062
Dimitris MossialosDepartment of Biochemistry and Biotechnology, University of Thessaly, Biopolis-Mezurlo, 41500 Larisa, Greece.ORCID 0000-0003-3753-4287
Bas van WijkDepartment of Dentistry, Radboud University Medical Center, Philips van Leydenlaan 25, 6525 EX Nijmegen, The Netherlands.
Petra NovakovaLERAM Pharmaceuticals s.r.o., Páteřní 1216/7, 63500 Brno, Czech Republic.
Frank A D T G WagenerDepartment of Dentistry, Radboud University Medical Center, Philips van Leydenlaan 25, 6525 EX Nijmegen, The Netherlands.ORCID 0000-0003-4837-1559
Niels A J CremersTriticum Exploitatie BV, Sleperweg 44, 6222 NK Maastricht, The Netherlands.ORCID 0000-0003-4042-8987
Radboud University Nijmegen · NLDubai Hospital · AEUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold sores are nasolabial blisters caused by herpes simplex virus (HSV) infections. Novel therapies demonstrating simultaneously antiviral activity and improved wound healing are warranted. The aim of this study was to investigate the efficacy of medical-grade honey (MGH) for treating HSV-induced cold sores. A crossover trial was performed in patients with recurrent cold sores (

Indexed as

cold soresherpes simplex virusitchmedical-grade honeypainwounds

Identifiers

PMID34959664
PMCPMC8706154
OpenAlexW4200363719

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.