Evidence map›Paper›PMID 34960039›Full record

ArticleNutrients2021

The Vitamin D Decrease in Children with Obesity Is Associated with the Development of Insulin Resistance during Puberty: The PUBMEP Study.

Liliane Viana Pires, Esther M González-Gil, Augusto Anguita-Ruiz, Gloria Bueno, Mercedes Gil-Campos, Rocío Vázquez-Cobela, Alexandra Pérez-Ferreirós, Luis A Moreno, Ángel Gil, Rosaura Leis and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Liliane Viana PiresDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0003-1710-0836
Esther M González-GilDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.
Augusto Anguita-RuizDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-6888-1041
Gloria BuenoGrowth, Exercise, Nutrition and Development (GENUD) Research Group, University of Zaragoza, 50009 Zaragoza, Spain.
Mercedes Gil-CamposCIBEROBN (Physiopathology of Obesity and Nutrition), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0002-9007-0242
Rocío Vázquez-CobelaCIBEROBN (Physiopathology of Obesity and Nutrition), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0002-3155-1601
Alexandra Pérez-FerreirósUnit of Investigation in Nutrition, Growth and Human Development of Galicia, Pediatric Department (USC), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University Clinical Hospital, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-7482-4374
Luis A MorenoGrowth, Exercise, Nutrition and Development (GENUD) Research Group, University of Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-0454-653X
Ángel GilDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0001-7663-0939
Rosaura LeisCIBEROBN (Physiopathology of Obesity and Nutrition), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0002-0540-4210
Concepción M AguileraDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-1451-4788

Funding

Instituto de Salud Carlos III PI11/01425, PI11/02042, PI11/02059, PI16/01301, PI16/01205, PI16/00871 and PI20/00563Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition CB15/00131, CB15/00043
6 · The paper itself

Abstract

Obesity and cardiometabolic risk have been associated with vitamin D levels even in children. The objective of the present study was to evaluate the association between insulin resistance (IR), cardiometabolic risk factors, and vitamin D in children from prepubertal to pubertal stages. A total of 76 children from the PUBMEP study, aged 4-12 years at baseline, were included. Children were evaluated in prepubertal and pubertal stages. Anthropometric measurements and selected cardiometabolic risk biomarkers, such as plasma glucose, blood lipids, insulin, adiponectin, leptin, and blood pressure, and serum 25-hydroxyvitamin D (25(OH)D) were determined. Children were categorized by obesity degree and IR status combined before and after puberty. Paired

Indexed as

Cardiometabolic Risk FactorsInsulin ResistanceAdolescentChildChild, PreschoolFemaleHumansMaleNutritional StatusPediatric ObesityPubertyVitamin D25-hydroxyvitamin DVitamin Dcardiometabolic risk factorschildinsulin resistanceobesitypubertyvitamin D

Identifiers

PMID34960039
PMCPMC8709093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.