ArticleMolecular biology and evolution2022
Evolution of Olfactory Receptors Tuned to Mustard Oils in Herbivorous Drosophilidae.
Article in Molecular biology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Genomic Identification and Comparative Characterization of Chemosensory Genes in Two Walnut Pests.Biology · 2026Article
- Receptor sequence divergence, gain, loss, duplication, and neofunctionalization drive olfactory adaptation inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genomic plasticity drives olfactory adaptation in a pest fly.bioRxiv : the preprint server for biology · 2025Article
- Odorant Receptors Mediating Avoidance of Toxic Mustard Oils in Drosophila melanogaster Are Expanded in Herbivorous Relatives.Molecular biology and evolution · 2025Article
- Shifts in bee diet breadths are associated with gene gains and losses and positive selection across olfactory receptors.G3 (Bethesda, Md.) · 2025Article
- Alternative Splicing in TRPA1 Drives Sensory Adaptation to Electrophiles in Drosophilids.bioRxiv : the preprint server for biology · 2025Article
- Functional characterization and evolution of olfactory responses in coeloconic sensilla of the global fruit pest Drosophila suzukii.BMC biology · 2025Article
- Preference for and resistance to a toxic sulfur volatile opens up a unique niche in Drosophila busckii.Nature communications · 2025Article
- Gene expansion in the hawkmothiScience · 2024Article
- Article
- Insights into the evolution of herbivory from a leaf-mining fly.Ecosphere (Washington, D.C) · 2024Article
- Taste evolution in an herbivorous drosophilid.bioRxiv : the preprint server for biology · 2024Article
- The power of Drosophila genetics in studying insect toxicology and chemical ecology.Crop health · 2023Review
- Evolution of chemosensory and detoxification gene families across herbivorous Drosophilidae.G3 (Bethesda, Md.) · 2023Article
- Evolution of chemosensory and detoxification gene families across herbivorous Drosophilidae.bioRxiv : the preprint server for biology · 2023Article
- Taste adaptations associated with host specialization in the specialist Drosophila sechellia.The Journal of experimental biology · 2023Article
- Review
- Article
- Molecular tug-of-war: Plant immune recognition of herbivory.The Plant cell · 2022Review
- Chemosensory protein 4 is required forFrontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The diversity of herbivorous insects is attributed to their propensity to specialize on toxic plants. In an evolutionary twist, toxins betray the identity of their bearers when herbivores coopt them as cues for host-plant finding, but the evolutionary mechanisms underlying this phenomenon are poorly understood. We focused on Scaptomyza flava, an herbivorous drosophilid specialized on isothiocyanate (ITC)-producing (Brassicales) plants, and identified Or67b paralogs that were triplicated as mustard-specific herbivory evolved. Using in vivo heterologous systems for the expression of olfactory receptors, we found that S. flava Or67bs, but not the homologs from microbe-feeding relatives, responded selectively to ITCs, each paralog detecting different ITC subsets. Consistent with this, S. flava was attracted to ITCs, as was Drosophila melanogaster expressing S. flava Or67b3 in the homologous Or67b olfactory circuit. ITCs were likely coopted as olfactory attractants through gene duplication and functional specialization (neofunctionalization and subfunctionalization) in S. flava, a recently derived herbivore.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.