Evidence map›Paper›PMID 34970915›Full record

ReviewJournal of the American Heart Association2022

Role of Multimodality Imaging in the Assessment of Myocardial Infarction With Nonobstructive Coronary Arteries: Beyond Conventional Coronary Angiography.

Brent Gudenkauf, Allison G Hays, Jacqueline Tamis-Holland, Jeffrey Trost, Daniel I Ambinder, Katherine C Wu, Armin Arbab-Zadeh, Roger S Blumenthal, Garima Sharma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  11. Review
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  15. Review
  16. Review
  17. MINOCA: Myocardial infarction no obstructive coronary artery disease.American heart journal plus : cardiology research and practice · 2023
    Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brent GudenkaufDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0003-0642-9935
Allison G HaysDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0003-2138-1589
Jacqueline Tamis-HollandDivision of Cardiology Mount Sinai- Morning Side New York City NY.
Jeffrey TrostDivision of Cardiology Johns Hopkins University School of Medicine Baltimore MD.
Daniel I AmbinderDivision of Cardiology Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0002-5875-4214
Katherine C WuDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0003-4958-5145
Armin Arbab-ZadehDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.
Roger S BlumenthalDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0003-1910-3168
Garima SharmaDivision of Cardiology Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore MD.ORCID 0000-0001-7254-2077

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction with nonobstructive coronary arteries (MINOCA) is a heterogeneous clinical entity, encompassing multiple different causes, and a cause of substantial morbidity and mortality. Current guidelines suggest a multimodality imaging approach in establishing the underlying cause for MINOCA, which is considered a working diagnosis. Recent studies have suggested that an initial workup consisting of cardiac magnetic resonance and invasive coronary imaging can yield the diagnosis in most patients. Cardiac magnetic resonance is particularly helpful in excluding nonischemic causes that can mimic MINOCA including myocarditis and Takotsubo cardiomyopathy, as well as for long-term prognostication. Additionally, intracoronary imaging with intravascular ultrasound or optical coherence tomography may be warranted to evaluate plaque composition, or evaluate for plaque disruption or spontaneous coronary dissection. The role of noninvasive imaging modalities such as coronary computed tomography angiography is currently being investigated in the diagnostic approach and follow-up of MINOCA and may be appropriate in lieu of invasive coronary angiography in select patients. In recent years, many strides have been made in the workup of MINOCA; however, significant knowledge gaps remain in the field, particularly in terms of treatment strategies. In this review, we summarize recent society guideline recommendations and consensus statements on the initial evaluation of MINOCA, review contemporary multimodality imaging approaches, and discuss treatment strategies including an ongoing clinical trial.

Indexed as

Coronary Artery DiseaseMyocardial InfarctionPlaque, AtheroscleroticCoronary AngiographyCoronary VesselsHumansMINOCAangiographycomputerized tomographymagnetic resonance imagingmyocardial infarctionoptical coherence tomography

Identifiers

PMID34970915
PMCPMC9075186

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.