Evidence map›Paper›PMID 34974339›Full record

ReviewJournal de mycologie medicale2022

Invasive Candida kefyr infection presenting as pyelonephritis in an ICU hospitalized COVID-19 patient: Case report and review of the literature.

Anastasia Spiliopoulou, Fevronia Kolonitsiou, Georgia Vrioni, Stamatia Tsoupra, Alexandra Lekkou, Fotini Paliogianni

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Journal de mycologie medicale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. An update on clinically relevant, rare, and emergingClinical microbiology reviews · 2025
    Review
  3. Article
  4. Review
  5. Global Epidemiology of Invasive Infections by UncommonJournal of fungi (Basel, Switzerland) · 2024
    Review
  6. Concerning the presumptive identification of Candida kefyr on Uriselect™4 agar.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Article
  7. Antifungal Drug Susceptibility Profile ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  8. Article
  9. Candidiasis and Other Emerging Yeasts.Current fungal infection reports · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anastasia SpiliopoulouDepartment of Microbiology, University Hospital of Patras, Patras, Greece.
Fevronia KolonitsiouDepartment of Microbiology, University Hospital of Patras, Patras, Greece.
Georgia VrioniDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Stamatia TsoupraDepartment of Internal Medicine, University Hospital of Patras, Greece.
Alexandra LekkouDepartment of Internal Medicine, Division of Infectious Diseases, University Hospital of Patras, Greece.
Fotini PaliogianniDepartment of Microbiology, University Hospital of Patras, Patras, Greece.
General University Hospital of Patras · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida kefyr (Kluyveromyces marxianus), an ascomycetous environmental yeast, occasionally isolated from dairy products, represents an uncommon but emerging pathogen in immunocompromised patients. Herein, we present a case of C. kefyr pyelonephritis in a 41-year-old, previously immunocompetent, patient who was hospitalized in an COVID-19 ICU. Pyelonephritis was associated with caliectasis and obstruction due to possible fungus ball formation. Predisposing factors included ICU stay, use of broad spectrum antibiotics and steroids, central venous catheterization, mechanical ventilation and urologic manipulation. Susceptibility testing revealed high MIC values to amphotericin B. Infection was effectively controlled by prolonged administration of fluconazole without further surgical intervention. COVID-19 complicated with invasive candidiasis is an increasingly observed clinical situation that warrants high suspicion index and careful evaluation of laboratory data.

Indexed as

Candidiasis, InvasiveCOVID-19PyelonephritisAdultAntifungal AgentsCandidaCandidiasisFluconazoleHumansIntensive Care UnitsKluyveromycesAntifungal AgentsFluconazoleCandida kefyrCOVID-19ICUInvasive candidiasisPyelonephritisUrinary tract infection

Identifiers

PMID34974339
PMCPMC8694783
OpenAlexW4200023566

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.