Evidence map›Paper›PMID 34975523›Full record

ArticleFrontiers in physiology2021

Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure.

Andrea K Brown, Alyssa Nichols, Chantell A Coley, Ubong S Ekperikpe, Kasi C McPherson, Corbin A Shields, Bibek Poudel, Denise C Cornelius, Jan M Williams

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Kidney Considerations in Pediatric Obesity.Current obesity reports · 2023
    Review
  4. Article
  5. Article
  6. Neutralizing MIP3The Journal of pharmacology and experimental therapeutics · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andrea K BrownDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Alyssa NicholsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Chantell A ColeyDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Ubong S EkperikpeDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Kasi C McPhersonDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Corbin A ShieldsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Bibek PoudelDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Denise C CorneliusDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
Jan M WilliamsDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS, United States.
University of Mississippi Medical Center · US

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Hypertension, Inflammation, and Vascular FunctionR01HL151407 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI CORNELIUS, DENISE CRESHUN · 2020 to 2024
$1.9M
Mechanisms involved in the early development of renal disease associated with prepubertal obesityR01DK109133 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI WILLIAMS, JAN MICHAEL · 2017 to 2021
$1.7M
NHLBI NIH HHS R01 HL151407NHLBI NIH HHS T32 HL105324NIDDK NIH HHS R01 DK109133NIGMS NIH HHS P20 GM103476
6 · The paper itself

Abstract

Recently, we reported that obese Dahl salt-sensitive leptin receptor mutant (SS

Indexed as

ACE inhibitorcytokinesGFRobesityproteinuriaSSLepRmutant ratSS rat

Identifiers

PMID34975523
PMCPMC8719629
OpenAlexW4200483491

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.