Evidence map›Paper›PMID 34976301›Full record

ReviewOxidative medicine and cellular longevity2021

The Oxidative Stress and Chronic Inflammatory Process in Chagas Disease: Role of Exosomes and Contributing Genetic Factors.

Edio Maldonado, Diego A Rojas, Fabiola Urbina, Aldo Solari

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Placental Barrier Breakdown Induced byInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Coinfection by multipleMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  5. An Update on Vaccines AgainstPathogens (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Chronic Chagasic Cardiomyopathy: Influence of Physical Exercise.Arquivos brasileiros de cardiologia · 2024
    Article
  9. Article
  10. Article
  11. The roles of COX-2 in protozoan infection.Frontiers in immunology · 2023
    Review
  12. Article
  13. Article
  14. Cellular Stress and Senescence Induction duringTropical medicine and infectious disease · 2022
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Edio MaldonadoPrograma Biología Celular y Molecular, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0001-7088-0806
Diego A RojasInstituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-5388-1070
Fabiola UrbinaPrograma Biología Celular y Molecular, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0003-2820-7356
Aldo SolariPrograma Biología Celular y Molecular, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0001-6968-4840
University of Chile · CLUniversidad Autónoma de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease is a neglected tropical disease caused by the flagellated protozoa

Indexed as

AnimalsChagas DiseaseChronic DiseaseExosomesHumansInflammationMiceOxidative StressReactive Oxygen SpeciesReactive Oxygen Species

Identifiers

PMID34976301
PMCPMC8718323
OpenAlexW4200487745

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.