Evidence map›Paper›PMID 34980451›Full record

ArticleJournal of vascular and interventional radiology : JVIR2022

Identifying the Ideal Target Vessel Size for Bariatric Embolization: Histologic Analysis of Swine and Human Gastric Fundi.

Jenanan Vairavamurthy, Frank Yuan, Robert A Anders, Dara L Kraitchman, Clifford R Weiss

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jenanan VairavamurthyDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California.
Frank YuanVascular and Interventional Radiology Center, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital/The Johns Hopkins University, Baltimore, Maryland.
Robert A AndersDepartment of Pathology, The Johns Hopkins Hospital/The Johns Hopkins University, Baltimore, Maryland.
Dara L KraitchmanDivision of MR Research, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital/The Johns Hopkins University, Baltimore, Maryland.
Clifford R WeissVascular and Interventional Radiology Center, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital/The Johns Hopkins University, Baltimore, Maryland. Electronic address: cweiss@jhmi.edu.
Johns Hopkins University · USUniversity of Southern California · US

Funding

QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Training for Clinician Scientists in Imaging ResearchT32EB006351 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI POMPER, MARTIN G · 2006 to 2022
$4.0M
Image-guided Bariatric Arterial Embolization (BAE) for the Treatment of ObesityR01EB017615 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI KRAITCHMAN, DARA L, WEISS, CLIFFORD RAABE · 2013 to 2016
$1.4M
NCATS NIH HHS UL1 TR003098NIBIB NIH HHS R01 EB017615NIBIB NIH HHS T32 EB006351
6 · The paper itself

Abstract

This study aimed to identify the ideal arteriole size to target in bariatric embolization, with the goal of maximizing weight loss efficacy while maintaining patient safety. Although all published clinical trials of bariatric embolization have used embolic microspheres that were at least 300 μm in diameter, optimal weight loss outcomes have been achieved safely in swine using 50-μm embolics. Human fundal remnants from bariatric surgery were compared with swine fundal sections after bariatric embolization with 50-μm embolic microspheres to assess the ideal fundal vessel size for bariatric embolization. In swine, the 50-μm embolic microspheres deposited in the luminal half of the submucosa with a mean arteriole size of 49 μm ± 30. The mean arteriole diameter in the corresponding submucosal layer of the human gastric fundi was 40 μm ± 30. These measurements may inform future clinical trials and direct the development of embolic agents for bariatric embolization.

Indexed as

BariatricsEmbolization, TherapeuticAnimalsGastric FundusHumansMicrospheresSwineWeight Loss

Identifiers

PMID34980451
PMCPMC8740629
OpenAlexW4205377078

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.