Evidence map›Paper›PMID 34984977›Full record

ArticleeLife2022

Functional profiling of long intergenic non-coding RNAs in fission yeast.

Maria Rodriguez-Lopez, Shajahan Anver, Cristina Cotobal, Stephan Kamrad, Michal Malecki, Clara Correia-Melo, Mimoza Hoti, StJohn Townsend, Samuel Marguerat, Sheng Kai Pong and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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  6. RiboCop surveils pre-rRNA processing by Dicer in cellular quiescence.bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Maria Rodriguez-LopezUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-2066-0589
Shajahan Anver *University College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-7582-5125
Cristina Cotobal *University College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.
Stephan Kamrad *University College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-5957-4661
Michal Malecki *University College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-1525-5036
Clara Correia-MeloThe Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom.ORCID 0000-0001-6062-1472
Mimoza HotiUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.
StJohn TownsendUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.
Samuel MargueratUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-2402-3165
Sheng Kai PongUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0002-9940-1175
Mary Y WuThe Francis Crick Institute, High Throughput Screening, London, United Kingdom.ORCID 0000-0002-2074-6171
Luis MontemayorUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.
Michael HowellThe Francis Crick Institute, High Throughput Screening, London, United Kingdom.ORCID 0000-0003-0912-0079
Markus RalserThe Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London, United Kingdom.
Jürg BählerUniversity College London, Institute of Healthy Ageing and Department of Genetics, Evolution & Environment, London, United Kingdom.ORCID 0000-0003-4036-1532
University College London · GBThe Francis Crick Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R009597/1Biotechnology and Biological Sciences Research Council BB/R018219/1Cancer Research UK FC001134Medical Research Council FC001134Medical Research Council MC_UP_1102/8Wellcome 095598/Z/11/ZWellcome Trust FC001134
6 · The paper itself

Abstract

Eukaryotic genomes express numerous long intergenic non-coding RNAs (lincRNAs) that do not overlap any coding genes. Some lincRNAs function in various aspects of gene regulation, but it is not clear in general to what extent lincRNAs contribute to the information flow from genotype to phenotype. To explore this question, we systematically analysed cellular roles of lincRNAs in

Indexed as

RNA, FungalRNA, UntranslatedSchizosaccharomycesRNA, FungalRNA, Untranslatedgene regulationgeneticsgenomicshigh-throughput phenotypinglong non-coding RNAphenomicsRNA functionS. pombe

Identifiers

PMID34984977
PMCPMC8730722
OpenAlexW4220753864

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.