Evidence map›Paper›PMID 34987600›Full record

ArticleComputational and mathematical methods in medicine2021

Neural Function Recovery and Safety of Mild Hypothermia Therapy Combined with Monosialotetrahexosylganglioside on Neonatal Asphyxia Complicated by Hypoxic Ischemic Encephalopathy.

Jingjing Ge, Xiaoling Jiao, Fanlin Qi, Hui Li

RetractedOpen access · hybridAbstract readControlled Clinical TrialRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jingjing GeDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264001, Shandong Province, China.
Xiaoling JiaoDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264001, Shandong Province, China.
Fanlin QiDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264001, Shandong Province, China.
Hui LiDepartment of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264001, Shandong Province, China.ORCID https://orcid.org/0000-0001-7203-1525
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the effect and safety of mild hypothermia therapy combined with monosialotetrahexosylganglioside (GM1) on neural function recovery of neonatal asphyxia complicated by hypoxic ischemic encephalopathy (HIE).

methodsThe clinical data of 90 neonates with HIE were retrospectively analyzed. According to the treatment methods, the neonates were divided into a routine group, a mild hypothermia group, and a combination group, with 30 cases in each group. The differences in neural function recovery, biochemical indexes, clinical signs recovery, efficacy, and complications were observed in the three groups after treatment.

resultsAfter treatment, the score of neonatal behavioral neurological assessment (NBNA) and level of superoxide dismutase (SOD) in the combination group were higher than those of the other two groups (

conclusionMild hypothermia therapy combined with GM1 for the treatment of neonatal asphyxia complicated by HIE can promote the recovery of neural function and reduce the incidence of complications in neonates.

Indexed as

Asphyxia NeonatorumBiomarkersCombined Modality TherapyComputational BiologyFemaleG(M1) GangliosideHumansHypothermia, InducedHypoxia-Ischemia, BrainInfant, NewbornMaleNeuropeptide YPhosphopyruvate HydrataseRecovery of FunctionRetrospective StudiesS100 Calcium Binding Protein beta SubunitBiomarkersG(M1) GangliosideNeuropeptide YPhosphopyruvate HydrataseS100B protein, humanS100 Calcium Binding Protein beta SubunitSuperoxide Dismutase

Identifiers

PMID34987600
PMCPMC8723842
OpenAlexW4206498825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.