Evidence map›Paper›PMID 34988242›Full record

ReviewOpen forum infectious diseases2021

On the Treatment of

Emily G McDonald, Guillaume Butler-Laporte, Olivier Del Corpo, Jimmy M Hsu, Alexander Lawandi, Julien Senecal, Zahra N Sohani, Matthew P Cheng, Todd C Lee

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07328984 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

How Long Should we Give Steroids for Patients With Severe PCP (HOW LONG)

TypeinterventionalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2026 to 2029Enrolled416ConditionsPneumocystis Pneumonia, Pneumocystis, Pneumocystis Jirovecii Infection, Pneumocystis Jiroveci PneumoniaArmsSystemic corticosteroids
NCT07357103 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) [A Branch of the Initial Treatment Domain of the SPIRIT-PCP Platform]

TypeinterventionalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2026 to 2029Enrolled416ConditionsPneumocystis, Pneumocystis Infection, Pneumocystis Carinii Infection, Pneumocystis CariniiArmsClindamycin + primaquine, Pentamidine, Atovaquone
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. JHLT open · 2025
    Article
  3. The 2025 EQUALJAC-antimicrobial resistance · 2025
    Article
  4. Review
  5. Review
  6. Pulmonary Coinfection ofOpen forum infectious diseases · 2025
    Article
  7. Article
  8. Article
  9. Cavitary lung lesions caused byBMJ case reports · 2024
    Article
  10. Article
  11. Clinical microbiology reviews · 2024
    Review
  12. Characterization of theAntimicrobial agents and chemotherapy · 2024
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily G McDonaldDivision of General Internal Medicine, Department of Medicine, McGill University Health Centre, Montréal, Canada.ORCID https://orcid.org/0000-0003-0783-0624
Guillaume Butler-LaporteDepartment of Epidemiology, Occupational Health, and Biostatistics, McGill University, Montréal, Canada.ORCID https://orcid.org/0000-0001-5388-0396
Olivier Del CorpoFaculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Jimmy M HsuFaculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Alexander LawandiDepartment of Critical Care Medicine, National Institutes of Health, Clinical Center, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0001-7948-3161
Julien SenecalFaculty of Medicine and Health Sciences, McGill University, Montréal, Canada.
Zahra N SohaniDepartment of Medicine, McGill University, Montréal, Canada.
Matthew P ChengDivision of Medical Microbiology, Department of Laboratory Medicine, McGill University Health Centre, Montréal, Canada.
Todd C LeeClinical Practice Assessment Unit, Department of Medicine, McGill University Health Centre, Montréal, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HIVimmunosuppressedopportunistic infectiousPneumocystis jirovecii pneumoniaTMP-SMX

Identifiers

PMID34988242
PMCPMC8694206

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.