ArticleESC heart failure2022
Left atrial strain predicts exercise capacity in heart failure independently of left ventricular ejection fraction.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- Left atrial dysfunction can independently predict exercise capacity in patients with chronic heart failure who use beta-blockers.BMC cardiovascular disorders · 2023Trial
- Prognostic significance of left atrial reservoir strain during exercise in patients with heart failure.International journal of cardiology. Heart & vasculature · 2026Article
- Left and Right Atrial Strain Across the Heart Failure Continuum: Multifaceted Markers of Subclinical Mechanical Dysfunction and Haemodynamic Burden.Diagnostics (Basel, Switzerland) · 2026Review
- Prognostic and functional value of left atrial indices in advanced heart failure.Cardiovascular ultrasound · 2026Article
- Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice.Reviews in cardiovascular medicine · 2025Review
- Assessing the Use of Left Atrial Strain Before and After Treadmill Exercise Stress Echocardiography.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Effects of Cardiac Contractility Modulation on Right Ventricular and Left Atrial Strain in Patients with Chronic Heart Failure.Journal of clinical medicine · 2025Article
- Time's imprint on the left atrium: aging and atrial myopathy.The journal of cardiovascular aging · 2025Article
- Left Atrial Strain-Current Review of Clinical Applications.Diagnostics (Basel, Switzerland) · 2025Review
- Atrial Strain as a Predictive Tool for Poor Exercise Capacity in Patients With Indeterminate Diastolic Function: The Utility and Challenges in Clinical Practice.Korean circulation journal · 2025Article
- Left Atrial Strain Predicts Poor Exercise Capacity in Patients With Indeterminate Diastolic Function.Korean circulation journal · 2025Article
- Atrial cardiomyopathy.ESC heart failure · 2025Article
- Left Atrial Strain in Patients with Chronic Heart Failure with Preserved Ejection Fraction: A Narrative Review.Life (Basel, Switzerland) · 2025Review
- Left Atrial Functional and Structural Characteristics in Patients After Total and Bicaval Orthotopic Heart Transplantation.Journal of clinical medicine · 2024Article
- Progress of echocardiography in the evaluation of left atrial function in patients with heart failure with preserved ejection fraction: a narrative review.Quantitative imaging in medicine and surgery · 2024Review
- Left atrial dysfunction relates to symptom onset in patients affected by severe degenerative mitral regurgitation.Cardiovascular ultrasound · 2024Article
- Atrial cardiomyopathy in endurance athletes.NPJ cardiovascular health · 2024Article
- Left atrial function during exercise stress echocardiography as a sign of paroxysmal/persistent atrial fibrillation.Cardiovascular ultrasound · 2024Article
- Usefulness of oxygen uptake efficiency slope in a 6 min walk test in chronic heart failure.ESC heart failure · 2024Article
- Incremental diagnostic and prognostic utility of left atrial deformation in heart failure using speckle tracking echocardiography.Heart failure reviews · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe hypothesized that left atrial (LA) remodelling and function are associated with poor exercise capacity as prognostic marker in chronic heart failure (CHF) across a broad range of left ventricular ejection fraction (LVEF). METHODS AND
resultsOne hundred seventy-one patients with CHF were analysed [age 65 ± 11 years, 136 males (80%); 86 heart failure with reduced ejection fraction (HFrEF), 27 heart failure with mid-range ejection fraction (HFmrEF), 58 heart failure with preserved ejection fraction (HFpEF)]. All patients underwent echocardiography and maximal cardiopulmonary exercise testing and were classified according to a prognostic cut-off of peak VO
conclusionsIn patients with CHF, an impaired LA reservoir function is independently associated with a severely reduced pVO
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.