Evidence mapPaperPMID 34991585Full record

ReviewBMC endocrine disorders2022

The many faces of diabetes. Is there a need for re-classification? A narrative review.

Nasser Sakran, Yitka Graham, Tadeja Pintar, Wah Yang, Radwan Kassir, Edith M Willigendael, Rishi Singhal, Zoë E Kooreman, Dharmanand Ramnarain, Kamal Mahawar and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Lycopene: A Potent Antioxidant with Multiple Health Benefits.Journal of nutrition and metabolism · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Intestinal Enteroendocrine Cells: Present and Future Druggable Targets.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Oxidative Regulation of Vascular CaAntioxidants (Basel, Switzerland) · 2022
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 7 countries.

Nasser SakranDepartment of Surgery, Holy Family Hospital, Nazareth, Israel.
Yitka GrahamFaculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.
Tadeja PintarDepartment of Abdominal Surgery, University Medical Center Ljubljana, Zaloška cesta, Ljubljana, Slovenia.
Wah YangDepartment of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, 613 Huangpu Avenue West, Guangzhou, Guangdong Province, China.
Radwan KassirCHU Félix Guyon, Allée des Topazes, Saint-Denis, France.
Edith M WilligendaelDepartment of Vascular Surgery, Medisch Spectrum Twente, Enschede, The Netherlands.
Rishi SinghalBariatric and Upper GI Unit, Birmingham Heartlands Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
Zoë E KooremanDepartment of Dermatology, Amphia Hospital, Breda, The Netherlands.
Dharmanand RamnarainDepartment of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands.
Kamal MahawarFaculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, UK.
Chetan ParmarDepartment of Surgery, Whittington Health NHS Trust, London, UK.
Brijesh MadhokEast Midlands Bariatric and Metabolic Institute, University Hospital of Derby and Burton NHS Foundation Trust, Burton, UK.
Sjaak PouwelsDepartment of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands. sjaakpwls@gmail.com.ORCID http://orcid.org/0000-0002-6390-7692
Amphia Ziekenhuis · NLBar-Ilan University · ILElisabeth-TweeSteden Ziekenhuis · NLFirst Affiliated Hospital of Jinan University · CNLjubljana University Medical Centre · SIMedisch Spectrum Twente · NLSouth Tyneside and Sunderland NHS Foundation Trust · GBSt. Elisabeth Hospital · CWUniversidad Anáhuac · MXUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity Hospitals of Derby and Burton NHS Foundation Trust · GBWhittington Health NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrounds and are difficult to classify. Bariatric surgery (BS) is considered the most effective treatment for obesity in terms of weight loss and comorbidity resolution, improves diabetes, and has been proven superior to medical management for the treatment of diabetes. The term metabolic surgery (MS) describes bariatric surgical procedures used primarily to treat T2DM and related metabolic conditions. MS is the most effective means of obtaining substantial and durable weight loss in individuals with obesity. Originally, BS was used as an alternative weight-loss therapy for patients with severe obesity, but clinical data revealed its metabolic benefits in patients with T2DM. MS is more effective than lifestyle or medical management in achieving glycaemic control, sustained weight loss, and reducing diabetes comorbidities. New guidelines for T2DM expand the use of MS to patients with a lower body mass index.Evidence has shown that endocrine changes resulting from BS translate into metabolic benefits that improve the comorbid conditions associated with obesity, such as hypertension, dyslipidemia, and T2DM. Other changes include bacterial flora rearrangement, bile acids secretion, and adipose tissue effect.This review aims to examine the physiological mechanisms in diabetes, risks for complications, the effects of bariatric and metabolic surgery and will shed light on whether diabetes should be reclassified.

Indexed as

Bariatric SurgeryBody Mass IndexComorbidityDiabetes ComplicationsDiabetes Mellitus, Type 2HumansRisk FactorsAntidiabetic drugsBariatric surgeryClassificationDiabetes mellitusGastrointestinal hormonesMetabolic surgery

Identifiers

PMID34991585
PMCPMC8740476
OpenAlexW4205846747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.