Evidence map›Paper›PMID 34991680›Full record

ArticleTrials2022

Nurse-led self-management support after organ transplantation-protocol of a multicentre, stepped-wedge randomized controlled trial.

Regina van Zanten, Monique van Dijk, Joost van Rosmalen, Denise Beck, Robert Zietse, Ann Van Hecke, AnneLoes van Staa, Emma K Massey, aanZET study group

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Survivorship interventions after liver transplantation (LT): A systematic review of interventions targeting physical and psychosocial well-being after LT.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Pooled it
  2. Nurse-Led Self-Management Support After Organ Transplantation - A Multicenter, Stepped-Wedge Randomized Controlled Trial.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Trial
  3. Psychosocial challenges with transplantation.Current opinion in pulmonary medicine · 2026
    Review
  4. Post-lung transplant surveillance in 2026: current practice, variability, and the need for standardization.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Regina van ZantenDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center, Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands. r.vanzanten@erasmusmc.nl.ORCID http://orcid.org/0000-0003-0002-6457
Monique van DijkDepartment of Internal Medicine, Nursing Studies, Erasmus Medical Center, Rotterdam, The Netherlands.
Joost van RosmalenDepartment of Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands.
Denise BeckDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center, Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Robert ZietseDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center, Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
Ann Van HeckeDepartment of Public Health and Primary Care, University Centre for Nursing and Midwifery, Ghent University Hospital, Ghent, Belgium.
AnneLoes van StaaUniversity of Applied Science Rotterdam, Rotterdam, The Netherlands.
Emma K MasseyDepartment of Internal Medicine, Erasmus MC Transplant Institute, University Medical Center, Dr. Molewaterplein 40, Rotterdam, 3015 GD, The Netherlands.
aanZET study group
Erasmus MC · NLGhent University Hospital · BERotterdam University of Applied Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecipients of an organ transplantation face a number of challenges and often need to change their health behaviour. Good self-management skills are essential for optimal clinical outcomes. However, few interventions are available to support post-transplant self-management. To fill this gap, we developed a self-management support intervention offered by nurse practitioners. The primary aim of the study is to implement and test the effectiveness of the ZENN intervention in promoting self-management skills among heart, kidney liver and lung transplant recipients in comparison to standard care. The secondary aim is to assess the self-management support skills of nurse practitioners who will deliver the intervention.

methodsThis multi-centre stepped-wedge randomized controlled trial will take place from September 2020 until May 2023. All departments will commence with inclusion of patients in the control period. Each department will be randomly assigned to a start date (step in the wedge) to commence the experimental period. Patients in the control period will receive standard care and will be asked to complete questionnaires at baseline (T0), 6 months (T1) and 12 months (T2), to assess self-management, self-regulation, quality of life and adherence. During the experimental period, patients will receive standard care plus the ZENN intervention and receive the same set of questionnaires as participants in the control period. Nurse practitioners will complete a baseline and follow-up questionnaire to assess differences in self-management support skills. Video recordings of outpatient clinic consultations during the control and experimental periods will determine the differences in nurses' needs-thwarting and needs-supporting skills between the control and experimental period. DISCUSSION: The ZENN intervention could be a useful approach to support patients' self-management skills after organ transplantation and thus promote clinical outcomes as well as avoid adverse events.

trial registrationDutch Trial Register NL8469 . Registered on March 19, 2020.

Indexed as

Organ TransplantationSelf-ManagementHumansMulticenter Studies as TopicNurse's RoleQuality of LifeRandomized Controlled Trials as TopicTransplant RecipientsBehaviour mechanismsGoalHolistic nursingMotivationNurse practitionersPatient participationPsychotherapySelf-controlSelf-efficacySelf-management

Identifiers

PMID34991680
PMCPMC8733435
OpenAlexW4205307343

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.