Evidence map›Paper›PMID 34994231›Full record

ArticleJournal of biological rhythms2022

Long-Term Imaging Reveals a Circadian Rhythm of Intracellular Chloride in Neurons of the Suprachiasmatic Nucleus.

Nathan J Klett, Olga Cravetchi, Charles N Allen

Open access · greenAbstract read
In one paragraph

Article in Journal of biological rhythms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. GABAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Nathan J KlettNeuroscience Graduate Program, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-7102-1728
Olga CravetchiOregon Institute for Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Charles N AllenOregon Institute for Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-3689-2878
Oregon Health & Science University · US

Funding

CELLULAR ELECTROPHYSIOLOGY OF THE SUPRACHIASMATIC NUCLEIR01NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 1998 to 2015
$4.4M
Mechanisms of GABAergic Signaling in the Suprachiasmatic Nucleus NetworkR01NS103842 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 2018 to 2025
$4.0M
Cellular Electrophysiology of the Suprachiasmatic NucleiR56NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 2011 to 2017
$1.1M
NINDS NIH HHS R01 NS036607NINDS NIH HHS R01 NS103842NINDS NIH HHS R56 NS036607
6 · The paper itself

Abstract

Both inhibitory and excitatory GABA transmission exist in the mature suprachiasmatic nucleus (SCN), the master pacemaker of circadian physiology. Whether GABA is inhibitory or excitatory depends on the intracellular chloride concentration ([Cl

Indexed as

ChloridesCircadian RhythmArginine Vasopressingamma-Aminobutyric AcidNeuronsSuprachiasmatic NucleusVasoactive Intestinal PeptideArginine VasopressinChloridesgamma-Aminobutyric AcidVasoactive Intestinal PeptidechlorideGABAsuprachiasmatic nucleusvasoactive intestinal peptidevasopressin

Identifiers

PMID34994231
PMCPMC9203244
OpenAlexW4205268505

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.