Evidence map›Paper›PMID 34996845›Full record

ArticleLife science alliance2022

Rbfox1 is required for myofibril development and maintaining fiber type-specific isoform expression in

Elena Nikonova, Amartya Mukherjee, Ketaki Kamble, Christiane Barz, Upendra Nongthomba, Maria L Spletter

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Elena NikonovaDepartment of Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität München, Martinsried-Planegg, Germany.
Amartya MukherjeeDepartment of Molecular Reproduction, Development and Genetics (MRDG), Indian Institute of Science, Bangalore, India.
Ketaki KambleDepartment of Molecular Reproduction, Development and Genetics (MRDG), Indian Institute of Science, Bangalore, India.
Christiane BarzMuscle Dynamics Group, Max Planck Institute of Biochemistry, Martinsried-Planegg, Germany.
Upendra NongthombaDepartment of Molecular Reproduction, Development and Genetics (MRDG), Indian Institute of Science, Bangalore, India upendra@iisc.ac.in.
Maria L SpletterDepartment of Physiological Chemistry, Biomedical Center, Ludwig-Maximilians-Universität München, Martinsried-Planegg, Germany maria.spletter@bmc.med.lmu.de.ORCID 0000-0002-2068-3350
Indian Institute of Science Bangalore · INLudwig-Maximilians-Universität München · DEMax Planck Institute of Biochemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein isoform transitions confer muscle fibers with distinct properties and are regulated by differential transcription and alternative splicing. RNA-binding Fox protein 1 (Rbfox1) can affect both transcript levels and splicing, and is known to contribute to normal muscle development and physiology in vertebrates, although the detailed mechanisms remain obscure. In this study, we report that Rbfox1 contributes to the generation of adult muscle diversity in

Indexed as

Drosophila ProteinsMyofibrilsRNA-Binding ProteinsAnimalsDrosophilaFemaleGene Knockdown TechniquesMaleProtein IsoformsDrosophila ProteinsProtein IsoformsRbfox1 protein, DrosophilaRNA-Binding Proteins

Identifiers

PMID34996845
PMCPMC8742874
OpenAlexW4220746157

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.