ArticleScientific reports2022
Radical pairs can explain magnetic field and lithium effects on the circadian clock.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Quantum theories of consciousness: a critical review of feasibility, philosophical sufficiency, and empirical testability.Frontiers in psychology · 2026Review
- Magnetoreceptive CRY/MagR complexes: linking circadian redox signalling to protein aggregation in Alzheimer's and Parkinson's disease.ADMET & DMPK · 2026Review
- Article
- Quantum Effects in Evolution: Terrestrial Fine-Tuning of Magnetic Parameters.Computational and structural biotechnology journal · 2026Article
- Are we trapped on Earth: space and accelerated ageing.NPJ microgravity · 2025Review
- Magnetic sense-dependent probabilistic decision-making in humans.Frontiers in neuroscience · 2025Article
- Quantum theory of a potential biological magnetic field sensor: Radical pair mechanism in flavin adenine dinucleotide biradicals.Computational and structural biotechnology journal · 2024Article
- Review
- Magnetic isotope effects: a potential testing ground for quantum biology.Frontiers in physiology · 2023Article
- Quantum based effects of therapeutic nuclear magnetic resonance persistently reduce glycolysis.iScience · 2022Article
- Radical triads, not pairs, may explain effects of hypomagnetic fields on neurogenesis.PLoS computational biology · 2022Article
- Magnetic field effects in biology from the perspective of the radical pair mechanism.Journal of the Royal Society, Interface · 2022Review
- Radical pairs may explain reactive oxygen species-mediated effects of hypomagnetic field on neurogenesis.PLoS computational biology · 2022Article
- Radical pairs may play a role in microtubule reorganization.Scientific reports · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drosophila's circadian clock can be perturbed by magnetic fields, as well as by lithium administration. Cryptochromes are critical for the circadian clock. Further, the radical pairs in cryptochrome also can explain magnetoreception in animals. Based on a simple radical pair mechanism model of the animal magnetic compass, we show that both magnetic fields and lithium can influence the spin dynamics of the naturally occurring radical pairs and hence modulate the circadian clock's rhythms. Using a simple chemical oscillator model for the circadian clock, we show that the spin dynamics influence a rate in the chemical oscillator model, which translates into a change in the circadian period. Our model can reproduce the results of two independent experiments, magnetic field and lithium effects on the circadian clock. Our model predicts that stronger magnetic fields would shorten the clock's period. We also predict that lithium influences the clock in an isotope-dependent manner. Furthermore, our model also predicts that magnetic fields and hyperfine interactions modulate oxidative stress. The findings of this work suggest that the quantum nature of radical pairs might play roles in the brain, as another piece of evidence in addition to recent results on xenon anesthesia and lithium effects on hyperactivity.
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