Evidence map›Paper›PMID 35000569›Full record

ArticlemAbs

Reproducibility and flexibility of monoclonal antibody production with

Kelsi Swope, Josh Morton, Gregory P Pogue, Leigh Burden, Nicholas Partain, Steve Hume, John Shepherd, Carrie A Simpson, Miles B Brennan, Thomas C Furman and 8 more

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in mAbs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Biotechnology reports (Amsterdam, Netherlands) · 2024
    Article
  10. Article
  11. Article
  12. Platform-Specific FcAntibodies (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Plant-based biopharmaceutical engineering.Nature reviews bioengineering · 2023
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Kelsi SwopeKentucky BioProcessing, Inc, Owensboro, KY, USA.
Josh MortonKentucky BioProcessing, Inc, Owensboro, KY, USA.
Gregory P PogueKentucky BioProcessing, Inc, Owensboro, KY, USA.
Leigh BurdenKentucky BioProcessing, Inc, Owensboro, KY, USA.
Nicholas PartainKentucky BioProcessing, Inc, Owensboro, KY, USA.
Steve HumeKentucky BioProcessing, Inc, Owensboro, KY, USA.
John ShepherdKentucky BioProcessing, Inc, Owensboro, KY, USA.
Carrie A SimpsonKentucky BioProcessing, Inc, Owensboro, KY, USA.
Miles B BrennanZabBio, Inc, San Diego, CA, USA.
Thomas C FurmanMapp Biopharmaceutical, Inc, San Diego, Ca, USA.
Sheila Kingrey-GebeMapp Biopharmaceutical, Inc, San Diego, Ca, USA.
Theresa MartinezMapp Biopharmaceutical, Inc, San Diego, Ca, USA.
Jim McDonoughMapp Biopharmaceutical, Inc, San Diego, Ca, USA.
Michael H PaulyZabBio, Inc, San Diego, CA, USA.
Kevin J WhaleyZabBio, Inc, San Diego, CA, USA.
Larry ZeitlinZabBio, Inc, San Diego, CA, USA.
Barry BratcherKentucky BioProcessing, Inc, Owensboro, KY, USA.
Hugh HaydonKentucky BioProcessing, Inc, Owensboro, KY, USA.
Mapp Biopharmaceutical (United States) · USThe University of Texas at Austin · US

Funding

HHS HHSO100201400009C
6 · The paper itself

Abstract

The ongoing SARS-CoV-2 coronavirus pandemic of 2020-2021 underscores the need for manufacturing platforms that can rapidly produce monoclonal antibody (mAb) therapies. As reported here, a platform based on

Indexed as

Antibodies, MonoclonalAntibodies, ViralNicotianaPlants, Genetically ModifiedCOVID-19COVID-19 Drug TreatmentHumansRecombinant ProteinsSARS-CoV-2Antibodies, MonoclonalAntibodies, ViralRecombinant Proteinsbiologicmonoclonal antibodyNicotiana benthamianaPlant made pharmaceuticals

Identifiers

PMID35000569
PMCPMC8744878
OpenAlexW4205336808

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.