Evidence map›Paper›PMID 35002697›Full record

ArticleFrontiers in pharmacology2021

A Traditional Chinese Medicine Plant Extract Prevents Alcohol-Induced Osteopenia.

Dongyang Qian, Hui Zhou, Pan Fan, Tao Yu, Anish Patel, Morgan O'Brien, Zhe Wang, Shiguang Lu, Guoqiang Tong, Yimin Shan and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Network Pharmacology Unveils Multi-Systemic Intervention ofEndocrine, metabolic & immune disorders drug targets · 2025
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  6. Review
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  8. The Role of Herbal Medicine in Modulating Bone Homeostasis.Current topics in medicinal chemistry · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Dongyang QianDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Hui ZhouJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Pan FanDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Tao YuDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Anish PatelDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Morgan O'BrienDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Zhe WangJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Shiguang LuJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Guoqiang TongJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Yimin ShanJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Lei WangJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Yuan GaoDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Yuan XiongDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Lily ZhangDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Xin WangDepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Yuancai LiuJing Brand Research Institute, Jing Brand Co., Ltd., Daye, China.
Shuanhu ZhouDepartment of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Harvard University, Boston, MA, United States.
Harvard University · USBrigham and Women's Hospital · USFirst Affiliated Hospital of Guangzhou Medical University · CNQilu Hospital of Shandong University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) has been practiced in the treatment of bone diseases and alcoholism. Chronic excessive alcohol use results in alcohol-induced bone diseases, including osteopenia and osteoporosis, which increases fracture risk, deficient bone repair, and osteonecrosis. This preclinical study investigated the therapeutic effects of TCM herbal extracts in animal models of chronic excessive alcohol consumption-induced osteopenia. TCM herbal extracts (Jing extracts) were prepared from nine Chinese herbal medicines, a combinative herbal formula for antifatigue and immune regulation, including

Indexed as

alcohol-induced bone diseasesethnopharmacologyosteoporosisTCM herbal extractstraditional Chinese medicine

Identifiers

PMID35002697
PMCPMC8730326
OpenAlexW4200190102

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.