Evidence map›Paper›PMID 35004232›Full record

ArticleMethodsX2022

Nitrocellulose redox permanganometry: A simple method for reductive capacity assessment.

Jan Homolak, Ivan Kodvanj, Ana Babic Perhoc, Davor Virag, Ana Knezovic, Jelena Osmanovic Barilar, Peter Riederer, Melita Salkovic-Petrisic

Abstract read
In one paragraph

Article in MethodsX, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan HomolakDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Ivan KodvanjDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Ana Babic PerhocDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Davor ViragDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Ana KnezovicDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Jelena Osmanovic BarilarDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.
Peter RiedererCenter of Mental Health, Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Würzburg, Würzburg, Germany.
Melita Salkovic-PetrisicDepartment of Pharmacology, University of Zagreb School of Medicine, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a rapid, simple, and robust method for measurement of the reductive capacity of liquid and solid biological samples based on potassium permanganate reduction followed by trapping of manganese dioxide precipitate on a nitrocellulose membrane. Moreover, we discuss how nitrocellulose redox permanganometry (NRP) can be used for high-throughput analysis of biological samples and present HistoNRP, its modification used for detailed analysis of reductive capacity spatial distribution in tissue with preserved anatomical relations.•NRP is a rapid, cost-effective, and simple method for reductive capacity assessment•NRP is compatible with a high-throughput screening of solid and liquid biological samples•HistoNRP exploits passive diffusion slice print blotting for reductive capacity spatial analysis.

Indexed as

AntioxidantNitrocelluloseOxidative stressPotassium permanganateReductive capacityROS

Identifiers

PMID35004232
PMCPMC8718987

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.