ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2021
Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- Measurement bias for age, sex, and years of education in selected RDoC tasks.Journal of clinical and experimental neuropsychology · 2026Article
- Adverse childhood experiences, early menopause, cognition, and dementia in older adults in the United States.Communications health · 2026Article
- Identifying lifestyle risk factors that discriminate memory trajectories: Differential findings across racial and ethnic groups in older adults.Neurobiology of aging · 2025Article
- Modeling the importance of life exposure factors on memory performance in diverse older adults: A machine learning approach.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Non-amnestic initial symptoms may be less prevalent in African American than White participants with Alzheimer's and mixed Lewy body and Alzheimer's pathology.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Retest reliability and reliable change of community-dwelling Black/African American older adults with and without mild cognitive impairment using NIH Toolbox-Cognition Battery and Cogstate Brief Battery for laptop.Journal of the International Neuropsychological Society : JINS · 2025Article
- Identification of amnestic mild cognitive impairment among Black and White community-dwelling older adults using NIH Toolbox Cognition tablet battery.Journal of the International Neuropsychological Society : JINS · 2024Article
- Multiple Chronic Conditions and Disability among Vietnamese Older Adults: Results from the Vietnamese Aging and Care Survey (VACS).Journal of racial and ethnic health disparities · 2024Article
- Racial and ethnic differences in the association between depressive symptoms and cognitive outcomes in older adults: Findings from KHANDLE and STAR.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Advancing public health: enabling culture-fair and education-independent automated cognitive assessment in low- and middle-income countries.Frontiers in public health · 2024Article
- Racial Differences in Clinical Presentation in Individuals Diagnosed With Frontotemporal Dementia.JAMA neurology · 2023Article
- Racial and Ethnic Differences in the Association between Depressive Symptoms and Cognitive Outcomes in Older Adults: Findings from KHANDLE and STAR.medRxiv : the preprint server for health sciences · 2023Article
- A Machine Learning Approach for Early Diagnosis of Cognitive Impairment Using Population-Based Data.Journal of Alzheimer's disease : JAD · 2023Article
- Accounting for lack of representation in dementia research: Generalizing KHANDLE study findings on the prevalence of cognitive impairment to the California older population.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Cognitive impairment in racially/ethnically diverse older adults: Accounting for sources of diagnostic bias.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
- Demographic predictors of cognitive performance in participants of a local substance abuse recovery program.Journal of Alzheimer's disease reportsArticle
- Racial/ethnic differences in neuropsychological test performance in frontotemporal degeneration.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Vietnamese Insights into Cognitive Aging Program (VIP): Objectives, study design, and cohort description.Alzheimer's & dementia (New York, N. Y.)Article
- The (in)visible Brazilians: A perspective review on the need for brain health and dementia research with Brazilian immigrants in the United States.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
introductionThe Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) study enrolled Asian, Black, Latino, and White adults ages 65+ without prior dementia diagnosis (N = 1709). We evaluated the prevalence of cognitive impairment (mild cognitive impairment or dementia) accounting for potential biases.
methodsA random subgroup (N = 541) received clinical evaluation and others were evaluated if they failed a cognitive screen. Diagnoses were made under two conditions: (1) demographics-blind, based on clinical exam and demographically adjusted neuropsychological test scores; and (2) all available information (clinical exam, demographics, and adjusted and unadjusted test scores).
resultsCognitive impairment prevalence was 28% for blinded-adjusted diagnosis and 25% using all available information. Black participants had higher impairment rates than White (both conditions) and Latino (blinded-adjusted diagnosis) participants. Incomplete assessments negatively biased prevalence estimates for White participants. DISCUSSION: Racial/ethnic disparities in cognitive impairment were amplified by attrition bias in White participants but were unaffected by type of test norms and diagnosticians' knowledge of demographics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.