Evidence map›Paper›PMID 35005447›Full record

ArticleJOR spine2021

Hydrogen sulfide regulates autophagy in nucleus pulposus cells under hypoxia.

Lei Yue, Yongkai Hu, Haoyong Fu, Longtao Qi, Haolin Sun

Open access · goldAbstract read
In one paragraph

Article in JOR spine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lei YueDepartment of Orthopaedics Peking University First Hospital, Peking University Beijing China.
Yongkai HuDepartment of Orthopedics General Hospital of Southern Theatre Command of PLA Guangzhou China.
Haoyong FuDepartment of Orthopaedics Peking University First Hospital, Peking University Beijing China.
Longtao QiDepartment of Orthopaedics Peking University First Hospital, Peking University Beijing China.
Haolin SunDepartment of Orthopaedics Peking University First Hospital, Peking University Beijing China.ORCID https://orcid.org/0000-0002-4938-9198
Peking University · CNThird Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHydrogen sulfide (H MATERIALS AND

methodsNP cells were isolated from rat caudal discs. Cobalt chloride was used to mimic hypoxia, sodium hydrosulfide was used to emulate exogenous H

resultsHypoxia markedly impaired NP cell proliferation compared with control. Whereas H

conclusionsOur results showed that H

Indexed as

autophagyhydrogen sulfidenucleus pulposus

Identifiers

PMID35005447
PMCPMC8717115
OpenAlexW4200255962

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.