ArticleiScience2022
Beat-to-beat dynamic regulation of intracellular pH in cardiomyocytes.
Open access · goldAbstract read
In one paragraph
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
What it found
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The trial behind it
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Exploring the Role of the SLC12A Cation-Coupled Chloride Cotransporters in the Cardiovascular System.Cells · 2026Review
- A Color-Tuning Bioluminescent Sensor (AmyLuc) for Real-Time Monitoring of Intracellular pH Dynamics in Cancer Cells.Analytical chemistry · 2026Article
- Panoramic voltage-sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras.The Journal of physiology · 2026Article
- Ablation of Slc26a6 Mitigates Myocardial Ischemia/Reperfusion Injury.Biomedicines · 2025Article
- CaBiomolecules · 2025Review
- Dissecting the pH Sensitivity of Kinesin-Driven Transport.The journal of physical chemistry. B · 2024Article
- Desmoplakin CSM models unravel mechanisms regulating the binding to intermediate filaments and putative therapeutics for cardiocutaneous diseases.Scientific reports · 2024Article
- The Structural-Functional Crosstalk of the Calsequestrin System: Insights and Pathological Implications.Biomolecules · 2023Review
- Development of a Chemogenetic Approach to Manipulate Intracellular pH.Journal of the American Chemical Society · 2023Article
- A novel method to extend viability and functionality of living heart slices.Frontiers in cardiovascular medicine · 2023Article
- Protocol to record and quantify the intracellular pH in contracting cardiomyocytes.STAR protocols · 2022Article
- INNOVATIVE TECHNIQUES AND NEW INSIGHTS: Studying cardiac ionic currents and action potentials in physiologically relevant conditions.Physiological mini-reviewsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Yankun LyuDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Phung N ThaiDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Lu RenDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Valeriy TimofeyevDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Zhong JianDepartment of Pharmacology, University of California, Davis, Davis, CA 95616, USA.
Seojin ParkDepartment of Physiology and Cell Biology, University of Nevada, Reno, Reno, NV 89557, USA.
Kenneth S GinsburgDepartment of Pharmacology, University of California, Davis, Davis, CA 95616, USA.
James OvertonDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Julie BossuytDepartment of Pharmacology, University of California, Davis, Davis, CA 95616, USA.
Donald M BersDepartment of Pharmacology, University of California, Davis, Davis, CA 95616, USA.
Ebenezer N YamoahDepartment of Physiology and Cell Biology, University of Nevada, Reno, Reno, NV 89557, USA.
Ye Chen-IzuDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Nipavan ChiamvimonvatDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
Xiao-Dong ZhangDepartment of Internal Medicine, University of California, Davis, Davis, CA 95616, USA.
University of California, Davis · USUniversity of Nevada, Reno · USVA Northern California Health Care System · US
Funding
Structural Analyses CoreP01AG051443 · NIA · UNIVERSITY OF NEVADA RENO · PI XIE, RUILI · 2016 to 2025
$15.5MFunctional Interactions of Cardiac Ion ChannelsR01HL085844 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2007 to 2025
$7.3MTraining Program In Basic & Translational Cardiovascular ScienceT32HL086350 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Martin Cadeiras, David A. Liem · 2008 to 2026
$7.1MTranslational Study of Cardiac DysfunctionR01HL085727 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN, SIRISH, PADMINI · 2008 to 2022
$5.7MPhospholemman and Na-Pump Function in Cardiac MyocytesR01HL081562 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M · 2005 to 2018
$5.3MInner ear ion channels in healthy and diseased conditionsR01DC016099 · NIDCD · UNIVERSITY OF NEVADA RENO · PI EBENEZER N YAMOAH · 2017 to 2026
$4.7MMechanical Load Effects on Cardiac Function and Heart DiseasesR35HL166575 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ye Chen-Izu · 2023 to 2026
$4.4MMECHANICAL LOAD EFFECT ON CARDIAC EXCITATION-CONTRACTION COUPLINGR01HL141460 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN-IZU, YE · 2019 to 2022
$2.6MMechanisms of Growth Factor Responsiveness in the Aging Auditory SystemR01AG060504 · NIA · UNIVERSITY OF NEVADA RENO · PI FRITZSCH, BERND, YAMOAH, EBENEZER N · 2018 to 2022
$2.5MDecoding the enigma of cardiac amplificationR01HL137228 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2020
$2.2MCalcium-dependent functions in Hair Cells and Spiral Ganglion NeuronsR01DC015135 · NIDCD · UNIVERSITY OF NEVADA RENO · PI GRATTON, MICHAEL ANNE NMI, YAMOAH, EBENEZER N · 2016 to 2020
$2.1MRegulation of hair cell functionsR01DC015252 · NIDCD · UNIVERSITY OF NEVADA RENO · PI YAMOAH, EBENEZER N · 2017 to 2021
$2.1MBLRD VA I01 BX000576CSRD VA I01 CX001490NHLBI NIH HHS F32 HL149288NHLBI NIH HHS R01 HL081562NHLBI NIH HHS R01 HL085727NHLBI NIH HHS R01 HL085844NHLBI NIH HHS R01 HL123526NHLBI NIH HHS R01 HL137228NHLBI NIH HHS R01 HL141460NHLBI NIH HHS R01 HL159993NHLBI NIH HHS R01 HL170520NHLBI NIH HHS R35 HL166575NHLBI NIH HHS R56 HL138392NHLBI NIH HHS T32 HL086350NIA NIH HHS P01 AG051443NIA NIH HHS R01 AG060504NIDCD NIH HHS R01 DC004215NIDCD NIH HHS R01 DC015135NIDCD NIH HHS R01 DC015252NIDCD NIH HHS R01 DC016099
Abstract
The mammalian heart beats incessantly with rhythmic mechanical activities generating acids that need to be buffered to maintain a stable intracellular pH (pH
Indexed as
Cardiovascular medicineMolecular biologyMolecular dynamics
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.