Evidence map›Paper›PMID 35010234›Full record

ReviewFoods (Basel, Switzerland)2022

Intestinal Organoids: New Tools to Comprehend the Virulence of Bacterial Foodborne Pathogens.

Mayra Aguirre Garcia, Killian Hillion, Jean-Michel Cappelier, Michel Neunlist, Maxime M Mahe, Nabila Haddad

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Safety evaluation ofCurrent research in food science · 2025
    Article
  3. Article
  4. Postbiotics fromFoods (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Cross-Talk Between the Intestinal Epithelium andFrontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mayra Aguirre GarciaUMR SECALIM, INRAE, Oniris, 44307 Nantes, France.ORCID 0000-0003-2129-0783
Killian HillionUMR Inserm 1235-TENS, INSERM, Université de Nantes, Institut des Maladies de l'Appareil Digestif-CHU de Nantes, 44035 Nantes, France.
Jean-Michel CappelierUMR SECALIM, INRAE, Oniris, 44307 Nantes, France.
Michel NeunlistUMR Inserm 1235-TENS, INSERM, Université de Nantes, Institut des Maladies de l'Appareil Digestif-CHU de Nantes, 44035 Nantes, France.
Maxime M MaheUMR Inserm 1235-TENS, INSERM, Université de Nantes, Institut des Maladies de l'Appareil Digestif-CHU de Nantes, 44035 Nantes, France.ORCID 0000-0003-2560-193X
Nabila HaddadUMR SECALIM, INRAE, Oniris, 44307 Nantes, France.

Funding

Agence Nationale de la Recherche #ANR-17-CE14-0021Bioregate Regenerative Medicine Cluster University of Nantes and Région Pays de la Loire ''New Team'' grantMaster Man-Imal IDEFI Laureat programme ANR-11-IDFI-0003National Research Institute for Agriculture, Food and Environment Campi-es project
6 · The paper itself

Abstract

Foodborne diseases cause high morbidity and mortality worldwide. Understanding the relationships between bacteria and epithelial cells throughout the infection process is essential to setting up preventive and therapeutic solutions. The extensive study of their pathophysiology has mostly been performed on transformed cell cultures that do not fully mirror the complex cell populations, the in vivo architectures, and the genetic profiles of native tissues. Following advances in primary cell culture techniques, organoids have been developed. Such technological breakthroughs have opened a new path in the study of microbial infectious diseases, and thus opened onto new strategies to control foodborne hazards. This review sheds new light on cellular messages from the host-foodborne pathogen crosstalk during in vitro organoid infection by the foodborne pathogenic bacteria with the highest health burden. Finally, future perspectives and current challenges are discussed to provide a better understanding of the potential applications of organoids in the investigation of foodborne infectious diseases.

Indexed as

enteroidsfoodborne bacteriain vitro cell modelsorganoidspathogenic mechanism

Identifiers

PMID35010234
PMCPMC8750402

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.