Evidence mapPaperPMID 35011940Full record

ArticleJournal of clinical medicine2021

Optical Coherence Tomography Angiography in Type 1 Diabetes Mellitus-Report 2: Diabetic Kidney Disease.

Aníbal Alé-Chilet, Carolina Bernal-Morales, Marina Barraso, Teresa Hernández, Cristian Oliva, Irene Vinagre, Emilio Ortega, Marc Figueras-Roca, Anna Sala-Puigdollers, Cristina Esquinas and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

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  14. State-of-the-Art Research on Diabetic Retinopathy.Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Aníbal Alé-ChiletInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0001-9479-4355
Carolina Bernal-MoralesInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0001-5469-3963
Marina BarrasoInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Teresa HernándezInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Cristian OlivaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Irene VinagreAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Emilio OrtegaAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0002-2217-8905
Marc Figueras-RocaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0002-0548-0539
Anna Sala-PuigdollersInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Cristina EsquinasRespiratory Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Marga GimenezAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Enric EsmatjesAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), 08036 Barcelona, Spain.
Alfredo AdánInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.
Javier Zarranz-VenturaInstitut Clínic d'Oftalmologia (ICOF), Hospital Clínic, 08028 Barcelona, Spain.ORCID 0000-0003-2338-8143
Hospital Clínic de Barcelona · ESCentro de Investigación Biomédica en Red · ESMoorfields Eye Hospital NHS Foundation Trust · GBVall d'Hebron Hospital Universitari · ES

Funding

Fundación La Marató TV3 201633.10Instituto de Salud Carlos III PI18/00518
6 · The paper itself

Abstract

The purpose of this study is to investigate potential associations between optical coherence tomography angiography (OCTA) parameters and diabetic kidney disease (DKD) categories in type 1 diabetes mellitus (T1DM) patients and controls. A complete ocular and systemic examination, including OCTA imaging tests and bloods, was performed. OCTA parameters included vessel density (VD), perfusion density (PD), foveal avascular zone area (FAZa), perimeter (FAZp) and circularity (FAZc) in the superficial vascular plexus, and DKD categories were defined according to glomerular filtration rate (GFR), albumin-creatinine ratio (ACR) and KDIGO prognosis risk classifications. A total of 425 individuals (1 eye/1 patient) were included. Reduced VD and FAZc were associated with greater categories of GFR (

Indexed as

diabetic kidney diseasediabetic nephropathyfoveal avascular zoneoculomicsoptical coherence tomography angiographyperfusion densityvessel density

Identifiers

PMID35011940
PMCPMC8745787
OpenAlexW4205458413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.